基础研究
Copyright ©The Author(s) 2012.
世界华人消化杂志. 2012-09-28; 20(27): 2562-2569
在线出版 2012-09-28. doi: 10.11569/wcjd.v20.i27.2562
表2 二乙基亚硝胺诱发大鼠肝细胞癌前病变的形态计量 (mean±SD, ni = 2)
剂量(mg/kg)时程(log(h))体积比
异型性指数(AI)癌变率(P/T)
汇管区(R1)肝索(R2) 肝细胞核(R3)
01.0569050.00090.39910.00090.00210/2
2.5408300.00090.42940.00100.00230/2
2.8346750.00110.50660.00150.00300/2
3.0083450.00110.51430.00170.00340/2
3.1320670.00200.56960.00190.00330/2
3.2282460.00200.57820.00220.00370/2
3.3069390.00350.41760.00160.00380/2
3.3735370.00330.48580.00190.00400/2
3.4312670.00340.50080.00210.00420/2
3.4822160.00350.51590.00310.00610/2
251.0569050.00090.45850.00090.00200/2
2.5408300.00100.51270.00100.00200/2
2.8346750.00130.55810.00200.00350/2
3.0083450.00180.57710.00310.00530/2
3.1320670.00230.64890.00420.00640/2
3.2282460.00330.65330.00570.00870/2
3.3069390.00350.66360.00590.00900/2
3.3735370.00390.66910.00610.00920/2
3.4312670.00410.68220.00730.01080/2
3.4822160.00430.69510.00810.01170/2
501.0569050.00060.47260.00130.00270/2
2.5408300.00320.42050.00140.00330/2
2.8346750.00860.52930.00240.00460/2
3.0083450.00920.59130.00510.00870/2
3.1320670.00950.68020.00610.00910/2
3.2282460.00980.67430.00750.01130/2
3.3069390.01010.70070.00860.01250/2
3.3735370.01070.63770.00920.01450/2
3.4312670.01490.82350.01180.01450/2
3.4822160.01550.79860.01220.01551/2
751.0569050.00080.50890.00150.00290/2
2.5408300.00180.53300.00190.00360/2
2.8346750.01110.61070.00540.00900/2
3.0083450.00920.68220.00710.01050/2
3.1320670.01090.78480.01060.01370/2
3.2282460.00970.77790.01330.01730/2
3.3069390.01160.80840.01460.01830/2
3.3735370.01240.76300.01640.02180/2
3.4312670.01720.83460.01780.02161/2
3.4822160.01790.83520.01840.02241/2
1001.0569050.00100.41290.00120.00300/2
2.5408300.00110.42410.00140.00320/2
2.8346750.00430.48330.00400.00830/2
3.0083450.00730.59000.00770.01310/2
3.1320670.01190.62940.00930.01500/2
3.2282460.01620.62300.01090.01780/2
3.3069390.01880.75280.01440.01950/2
3.3735370.01900.77510.01640.02161/2
3.4312670.02170.80120.01750.02242/2
3.4822160.02240.83470.01840.02252/2

引文著录: 宋艺君, 刘晓婷, 冯丽莉, 王湘, 白荟芳, 田民强, 张微, 祖承哲, 赵欣, 蔡大勇, 王玥琦. 二乙基亚硝胺诱发肝癌前病变大鼠模型的建立. 世界华人消化杂志 2012; 20(27): 2562-2569