Copyright
©The Author(s) 2012.
世界华人消化杂志. 2012-09-28; 20(27): 2562-2569
在线出版 2012-09-28. doi: 10.11569/wcjd.v20.i27.2562
在线出版 2012-09-28. doi: 10.11569/wcjd.v20.i27.2562
剂量(mg/kg) | 时程(log(h)) | 体积比 | 异型性指数(AI) | 癌变率(P/T) | ||
汇管区(R1) | 肝索(R2) 肝细胞核(R3) | |||||
0 | 1.056905 | 0.0009 | 0.3991 | 0.0009 | 0.0021 | 0/2 |
2.540830 | 0.0009 | 0.4294 | 0.0010 | 0.0023 | 0/2 | |
2.834675 | 0.0011 | 0.5066 | 0.0015 | 0.0030 | 0/2 | |
3.008345 | 0.0011 | 0.5143 | 0.0017 | 0.0034 | 0/2 | |
3.132067 | 0.0020 | 0.5696 | 0.0019 | 0.0033 | 0/2 | |
3.228246 | 0.0020 | 0.5782 | 0.0022 | 0.0037 | 0/2 | |
3.306939 | 0.0035 | 0.4176 | 0.0016 | 0.0038 | 0/2 | |
3.373537 | 0.0033 | 0.4858 | 0.0019 | 0.0040 | 0/2 | |
3.431267 | 0.0034 | 0.5008 | 0.0021 | 0.0042 | 0/2 | |
3.482216 | 0.0035 | 0.5159 | 0.0031 | 0.0061 | 0/2 | |
25 | 1.056905 | 0.0009 | 0.4585 | 0.0009 | 0.0020 | 0/2 |
2.540830 | 0.0010 | 0.5127 | 0.0010 | 0.0020 | 0/2 | |
2.834675 | 0.0013 | 0.5581 | 0.0020 | 0.0035 | 0/2 | |
3.008345 | 0.0018 | 0.5771 | 0.0031 | 0.0053 | 0/2 | |
3.132067 | 0.0023 | 0.6489 | 0.0042 | 0.0064 | 0/2 | |
3.228246 | 0.0033 | 0.6533 | 0.0057 | 0.0087 | 0/2 | |
3.306939 | 0.0035 | 0.6636 | 0.0059 | 0.0090 | 0/2 | |
3.373537 | 0.0039 | 0.6691 | 0.0061 | 0.0092 | 0/2 | |
3.431267 | 0.0041 | 0.6822 | 0.0073 | 0.0108 | 0/2 | |
3.482216 | 0.0043 | 0.6951 | 0.0081 | 0.0117 | 0/2 | |
50 | 1.056905 | 0.0006 | 0.4726 | 0.0013 | 0.0027 | 0/2 |
2.540830 | 0.0032 | 0.4205 | 0.0014 | 0.0033 | 0/2 | |
2.834675 | 0.0086 | 0.5293 | 0.0024 | 0.0046 | 0/2 | |
3.008345 | 0.0092 | 0.5913 | 0.0051 | 0.0087 | 0/2 | |
3.132067 | 0.0095 | 0.6802 | 0.0061 | 0.0091 | 0/2 | |
3.228246 | 0.0098 | 0.6743 | 0.0075 | 0.0113 | 0/2 | |
3.306939 | 0.0101 | 0.7007 | 0.0086 | 0.0125 | 0/2 | |
3.373537 | 0.0107 | 0.6377 | 0.0092 | 0.0145 | 0/2 | |
3.431267 | 0.0149 | 0.8235 | 0.0118 | 0.0145 | 0/2 | |
3.482216 | 0.0155 | 0.7986 | 0.0122 | 0.0155 | 1/2 | |
75 | 1.056905 | 0.0008 | 0.5089 | 0.0015 | 0.0029 | 0/2 |
2.540830 | 0.0018 | 0.5330 | 0.0019 | 0.0036 | 0/2 | |
2.834675 | 0.0111 | 0.6107 | 0.0054 | 0.0090 | 0/2 | |
3.008345 | 0.0092 | 0.6822 | 0.0071 | 0.0105 | 0/2 | |
3.132067 | 0.0109 | 0.7848 | 0.0106 | 0.0137 | 0/2 | |
3.228246 | 0.0097 | 0.7779 | 0.0133 | 0.0173 | 0/2 | |
3.306939 | 0.0116 | 0.8084 | 0.0146 | 0.0183 | 0/2 | |
3.373537 | 0.0124 | 0.7630 | 0.0164 | 0.0218 | 0/2 | |
3.431267 | 0.0172 | 0.8346 | 0.0178 | 0.0216 | 1/2 | |
3.482216 | 0.0179 | 0.8352 | 0.0184 | 0.0224 | 1/2 | |
100 | 1.056905 | 0.0010 | 0.4129 | 0.0012 | 0.0030 | 0/2 |
2.540830 | 0.0011 | 0.4241 | 0.0014 | 0.0032 | 0/2 | |
2.834675 | 0.0043 | 0.4833 | 0.0040 | 0.0083 | 0/2 | |
3.008345 | 0.0073 | 0.5900 | 0.0077 | 0.0131 | 0/2 | |
3.132067 | 0.0119 | 0.6294 | 0.0093 | 0.0150 | 0/2 | |
3.228246 | 0.0162 | 0.6230 | 0.0109 | 0.0178 | 0/2 | |
3.306939 | 0.0188 | 0.7528 | 0.0144 | 0.0195 | 0/2 | |
3.373537 | 0.0190 | 0.7751 | 0.0164 | 0.0216 | 1/2 | |
3.431267 | 0.0217 | 0.8012 | 0.0175 | 0.0224 | 2/2 | |
3.482216 | 0.0224 | 0.8347 | 0.0184 | 0.0225 | 2/2 |
引文著录: 宋艺君, 刘晓婷, 冯丽莉, 王湘, 白荟芳, 田民强, 张微, 祖承哲, 赵欣, 蔡大勇, 王玥琦. 二乙基亚硝胺诱发肝癌前病变大鼠模型的建立. 世界华人消化杂志 2012; 20(27): 2562-2569