临床经验
Copyright ©The Author(s) 2012.
世界华人消化杂志. 2012-04-08; 20(10): 875-882
在线出版 2012-04-08. doi: 10.11569/wcjd.v20.i10.875
表4 IL-17A/F基因多态性与CD临床表现之间的关系
nOR (95%CI)
rs2275913
rs8193036
rs3804513
rs763780
Allele AAA+AG vs GGAlleleTTT+CT vs CCAlleleTAT+TT vs AAAllele CCT+CC vs TT
病变范围
回肠210.820.692.193.010.960.941.962.27
(0.34-1.97)(0.19-2.50)(0.91-5.27)(0.76-11.82)(0.27-3.39)(0.24-3.76)(0.53-7.19)(0.55-9.32)
结肠220.991.921.081.581.211.26--
(0.43-2.31)(0.41-9.46)(0.43-2.71)(0.48-5.22)(0.39-3.74)(0.35-4.440--
回结肠371.182.240.990.920.870.843.60a4.95b
(0.61-1.29)(0.62-8.09)(0.47-2.09)(0.59-2.37)(0.32-2.35)(0.29-2.48)(1.51-8.60)(1.81-13.54)
临床严重程度
轻度240.842.481.491.971.490.951.241.35
(0.31-1.99)(0.51-12.06)(0.60-3.72)(0.55-7.05)(0.60-3.72)(0.24-3.76)(0.27-5.69)(0.27-6.71)
中度501.091.741.231.221.151.192.022.35
(0.59-1.99)(0.64-4.74)(0.62-2.37)(0.52-2.87)(0.50-2.65)(0.47-2.99)(0.81-5.06)(0.87-6.39)

引文著录: 于鹏丽, 张晓斐, 沈方程, 张红杰. IL-17基因多态性与中国汉族人群炎症性肠病的关系. 世界华人消化杂志 2012; 20(10): 875-882