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©The Author(s) 2012.
世界华人消化杂志. 2012-04-08; 20(10): 875-882
在线出版 2012-04-08. doi: 10.11569/wcjd.v20.i10.875
在线出版 2012-04-08. doi: 10.11569/wcjd.v20.i10.875
n | OR (95%CI) | ||||||||
rs2275913 | rs8193036 | rs3804513 | rs763780 | ||||||
Allele A | AA+AG vs GG | Allele | TTT+CT vs CC | Allele | TAT+TT vs AA | Allele C | CT+CC vs TT | ||
病变范围 | |||||||||
回肠 | 21 | 0.82 | 0.69 | 2.19 | 3.01 | 0.96 | 0.94 | 1.96 | 2.27 |
(0.34-1.97) | (0.19-2.50) | (0.91-5.27) | (0.76-11.82) | (0.27-3.39) | (0.24-3.76) | (0.53-7.19) | (0.55-9.32) | ||
结肠 | 22 | 0.99 | 1.92 | 1.08 | 1.58 | 1.21 | 1.26 | - | - |
(0.43-2.31) | (0.41-9.46) | (0.43-2.71) | (0.48-5.22) | (0.39-3.74) | (0.35-4.440 | - | - | ||
回结肠 | 37 | 1.18 | 2.24 | 0.99 | 0.92 | 0.87 | 0.84 | 3.60a | 4.95b |
(0.61-1.29) | (0.62-8.09) | (0.47-2.09) | (0.59-2.37) | (0.32-2.35) | (0.29-2.48) | (1.51-8.60) | (1.81-13.54) | ||
临床严重程度 | |||||||||
轻度 | 24 | 0.84 | 2.48 | 1.49 | 1.97 | 1.49 | 0.95 | 1.24 | 1.35 |
(0.31-1.99) | (0.51-12.06) | (0.60-3.72) | (0.55-7.05) | (0.60-3.72) | (0.24-3.76) | (0.27-5.69) | (0.27-6.71) | ||
中度 | 50 | 1.09 | 1.74 | 1.23 | 1.22 | 1.15 | 1.19 | 2.02 | 2.35 |
(0.59-1.99) | (0.64-4.74) | (0.62-2.37) | (0.52-2.87) | (0.50-2.65) | (0.47-2.99) | (0.81-5.06) | (0.87-6.39) |
引文著录: 于鹏丽, 张晓斐, 沈方程, 张红杰. IL-17基因多态性与中国汉族人群炎症性肠病的关系. 世界华人消化杂志 2012; 20(10): 875-882