IL-17基因多态性与中国汉族人群炎症性肠病的关系

表3 IL-17A/F基因多态性与UC临床表现之间的关系

	n	OR(95%CI)
		rs2275913		rs8193036		rs3804513		rs763780
		Allele A	AA+AG vs GG	Allele	TTT+CT vs CC	Allele	TAT+TT vs AA	Allele C	CT+CC vs TT
病变范围
直肠乙状结肠	108	1.06	1.25	1.01	1.13	0.98	0.84	1.41	1.55
		(0.67-1.65)	(0.60-2.59)	(0.61-1.66)	(0.59-2.12)	(0.51-1.89)	(0.43-1.81)	(0.65-3.04)	(0.68-3.52)
广泛 结肠	106	0.66	0.57	0.89	1.08	1.00	0.91	1.58	1.59
		(0.41-1.05)	(0.29-1.11)	(0.54-1.49)	(0.57-2.05)	(0.52-1.90)	(0.44-1.86)	(0.74-3.36)	(0.69-3.61)
左半 结肠	56	1.36	1.19	0.50	0.45	1.01	0.84	1.77	2.02
		(0.76-2.42)	(0.47-3.02)	(0.23-1.08)	(0.18-1.09)	(0.44-2.29)	(0.33-2.14)	(0.71-4.42)	(0.76-5.39)
临床严重程度
轻度	110	1.06	1.58	0.81	1.41	1.03	0.94	1.52	1.69
		(0.68-1.65)	(0.74-3.39)	(0.49-1.26)	(0.71-2.77)	(0.55-1.94)	(0.47-1.91)	(0.72-3.22)	(0.76-3.77)
中度	142	0.86	0.44a	1.14	1.09	0.82	0.74	1.58	1.62
		(0.57-1.30)	(0.23-0.83)	(0.73-1.78)	(0.62-1.95)	(0.45-1.52)	(0.38-1.44)	(0.79-3.14)	(0.77-3.43)
重度	18	0.75	0.21a	1.01	1.41	2.32	2.02	1.55	1.73
		(0.28-1.99)	(0.05-0.80)	(0.35-2.93)	(0.43-2.21)	(0.79-6.90)	(0.52-7.93)	(0.33-7.22)	(0.33-8.96)

^aP = 0.04, vs UC组.