Copyright
©The Author(s) 2011.
世界华人消化杂志. 2011-03-18; 19(8): 868-873
在线出版 2011-03-18. doi: 10.11569/wcjd.v19.i8.868
在线出版 2011-03-18. doi: 10.11569/wcjd.v19.i8.868
表4 仅在大肠腺癌中差异表达的肿瘤相关基因(-表示基因表达下调)
| GenBank序列号 | 基因功能 | 基因标签 | Ratio | |
| 大肠腺瘤 | 大肠腺癌 | |||
| NM001170341 | myeloid leukemia factor 2 | MLF2 | - | 2.05 |
| NM005438 | FOS-like antigen-1 | FOSL1 | - | 2.09 |
| BC059522 | ribosomal protein S30 | FAU | - | 2.12 |
| BC08072 | v-raf murine sarcoma 3611 viral oncogene homolog 1 | ARAF1 | - | 2.20 |
| NM020531 | chromosome 20open reading frame 3 | C20ORF3 | - | 2.23 |
| NM008583 | multiple endocrine neoplasia I | MEN1 | - | 2.23 |
| NM204434 | cyclin-dependent kinase inhibitor 2A | CDKN2A | - | 2.27 |
| NM133862 | fibrinogen, gamma polypeptide | FGG | - | 2.75 |
| BC162533 | GRO2 oncogene | GRO2 | - | 2.93 |
| NM011492 | serine/threonine kinase 11 (Peutz-Jeghers syndrome) | STK11 | - | 3.02 |
| NM205510 | fibroblast growth factor receptor 1 | FGFR1 | - | 3.52 |
| NM001040403 | prohibitin | PHB | - | 3.66 |
| NM00109824 | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | HRAS | - | 4.03 |
| NM001950 | E2F transcription factor 4,p107/p130-binding | E2F4 | - | 4.08 |
| NM001082478 | insulin-like growth factor 2 receptor | IGF2R | - | 4.17 |
| NM004448 | v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 | ERBB2 | - | 4.57 |
| NM001107159 | matrix metalloproteinase 19 | MMP19 | - | 4.60 |
| NM010658 | v-maf musculoaponeurotic fibrosarcoma oncogene family | MAFG | - | 4.85 |
| NM033158 | hyaluronoglucosaminidase 2 | HYAL2 | - | 5.26 |
| NM022012 | mitogen-activated protein kinase kinase kinase 11 | MAP3K11 | - | 5.34 |
| NM023983 | melanoma adhesion molecule | MCAM | - | 5.48 |
| NM001170716 | breast cancer anti-estrogen resistance 1 | BCAR1 | - | 6.16 |
| NM000535 | postmeiotic segregation increased (S. cerevisiae) 2 | PMS2 | - | 6.18 |
| BC046375 | P53-induced protein | PIG11 | - | 7.66 |
| NM001142573 | IMP (inosine monophosphate) dehydrogenase 1 | IMPDH1 | - | 7.67 |
| NM005380 | neuroblastoma, suppression of tumorigenicity 1 | NBL1 | - | 7.69 |
| NM003542 | H4 histone family, member G | H4FG | - | 8.13 |
| NM002466 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | MYBL2 | - | 10.76 |
| NM022588 | metastasis associated 1 | MTA1 | - | 12.03 |
| NM194359 | v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 | ERBB3 | - | -6.02 |
| L36953 | MAD (mothers against decapentaplegic) homolog 4 | MADH4 | - | -5.03 |
| NM005638 | ADP-ribosylation factor GTPase activating protein 1 | ARFGAP | - | -4.76 |
| NM032415 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | MALT1 | - | -3.27 |
| NM008284 | v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog | KRAS2 | - | -3.26 |
| XM002190948 | v-ral simian leukemia viral oncogene homolog B | RALB | - | -3.21 |
| NM003766 | coiled-coil, myosin-like BCL2-interacting protein | BECN1 | - | -3.15 |
| NM001005765 | RAP1A, member of RAS oncogene family | RAP1A | - | -3.08 |
| NM002439 | phosphatase and tensin homolog | PTEN | - | -3.05 |
| XM002084629 | TRK-fused gene | TFG | - | -3.03 |
| AY805747 | ras homolog gene family, member E | ARHE | - | -2.95 |
| NM001099373 | SET translocation | SET | - | -2.93 |
| NM053455 | fibrinogen-like 2 | FGL2 | - | -2.70 |
| NM012680 | tuberous sclerosis 1 | TSC1 | - | -2.67 |
| NM001146216 | transforming acidic coiled-coil containing protein 1 | TACC1 | - | -2.59 |
| NM017045 | retinoblastoma 1 (including osteosarcoma) | RB1 | - | -2.42 |
| NM133250 | mutS (E. coli) homolog 2 | MSH2 | - | -2.24 |
| NM005805 | cadherin 1, type 1, E-cadherin (epithelial) | CDH1 | - | -2.10 |
引文著录: 曾伟, 南清振, 戴益琛, 朱小三, 陈章兴, 谢军培, 傅育卡, 林园园. 大肠腺瘤与大肠腺癌肿瘤相关基因的差异表达. 世界华人消化杂志 2011; 19(8): 868-873