塞来昔布对大鼠重症急性胰腺炎的治疗作用

表2 大鼠血清TNF-α、IL-1β及IL-6浓度 (ng/L, mean±SD)

分组	时间点
	6 h	12 h	24 h
对照组
TNF-α	11.28±3.27	12.54±3.93	11.83±2.85
IL-1β	1.58±0.35	2.06±0.56	1.89±0.44
IL-6	38.42±6.54	50.80±11.20	45.63±9.78
SAP组
TNF-α	98.65±15.49	156.78±22.3	178.86±23.12
IL-1β	45.82±7.87	58.60±9.06	62.91±8.31
IL-6	134.69±18.52	142.54±21.97	160.47±23.86
SAP+塞来昔布低剂量治疗组
TNF-α	89.54±13.93	122.65±22.3a	133.27±23.12a
IL-1β	27.80±5.84a	33.5±11.04a	38.58±9.74a
IL-6	119.33±24.56	121.70±35.31a	152.53±31.69a
SAP+塞来昔布高剂量治疗组
TNF-α	54.65±8.62a	87.56±10.59a	86.65±7.76a
IL-1β	11.83±2.63a	13.42±3.59a	18.50±5.03a
IL-6	64.52±13.72a	67.80±20.07a	68.02±18.55a

^aP<0.05 vs SAP组.