Copyright
©The Author(s) 2008.
世界华人消化杂志. 2008-08-08; 16(22): 2537-2541
在线出版 2008-08-08. doi: 10.11569/wcjd.v16.i22.2537
在线出版 2008-08-08. doi: 10.11569/wcjd.v16.i22.2537
表1 在肝炎、肝硬化、肝癌中共同上调表达的基因
编号 | Gene代码 | 基因描述 | 染色体定位 | 比值 | ||
1 | Hs.534362 | Protease, serine, 1(trypsin 1), PRSS1 | 7q34 | 181.02 | ||
2 | Hs.9029 | Keratin 23(histone deacetylase inducible), KRT23 | 17q21.2 | 51.98 | ||
3 | Hs.20415 | Family with sequence similarity 3, member B, FAM3B | 21q22.3 | 42.22 | ||
4 | Hs.313 | Secreted phosphoprotein 1, SPP1 | 4q21-q25 | 39.40 | ||
5 | Hs.80962 | Neurotensin, NTS | 12q21 | 24.25 | ||
6 | Hs.5940 | Mucin 13, epithelial transmembrane, MUC13 | 3q13.3 | 22.63 | ||
7 | Hs.108106 | Ubiquitin-like, containing PHD and RING finger domains 1, UHRF1 | 19p13.3 | 22.63 | ||
8 | Hs.165636 | DIRAS family, GTP-binding RAS-like 2, DIRAS2 | 9q22.2 | 18.38 | ||
9 | Hs.692 | Tumor-associated calcium signal transducer 1,TACSTD1 | 2p21 | 16.00 | ||
10 | Hs.121017 | Histone 1, H2ae, HIST1H2AE | 6p22.2-p21.1 | 16.00 | ||
11 | Hs.237396 | Hypothetical protein LOC643911, LOC643911 | 16q12.2 | 34.00 | ||
12 | Hs.296341 | CAP, adenylate cyclase-associated protein, 2 (yeast), CAP2 | 6p22.3 | 16.00 | ||
13 | Hs.375108 | CD24 antigen(small cell lung carcinoma cluster 4 antigen), CD24 | 6q21 | 14.93 | ||
14 | Hs.421956 | Spindle pole body component 25 homolog, Spc25 | 2q24.3 | 14.93 | ||
15 | Hs.414467 | Homeo box A13, HOXA13 | 7p15-p14 | 14.93 | ||
16 | Hs.132748 | Ribosomal protein L39-like, RPL39L | 3q27 | 14.93 | ||
17 | Hs.352662 | Golgi phosphoprotein 2, GOLPH2 | 9q21.33 | 13.93 | ||
18 | Hs.528669 | Chromosome condensation protein G, HCAP-G | 4p15.33 | 10.20 | ||
19 | Hs.431270 | Chromosome 9 open reading frame 125, C9orf125 | 9q31.1 | 9.19 | ||
20 | Hs.458287 | N-acetyltransferase 8B, NAT8B | 2p13.1 | 8.57 | ||
21 | Hs.436170 | Nudix(nucleoside diphosphate linked moiety X)type motif 14, NUDT14 | 14q32.33 | 8.00 | ||
22 | Hs.65436 | Lysyl oxidase-like 1, LOXL1 | 15q22 | 6.96 | ||
23 | Hs.228320 | Chromosome 10 open reading frame 81, C10orf81 | 10q25.3 | 6.73 | ||
24 | Hs.182137 | Histone 1, H2bg, HIST1H2BG | 6p21.3 | 6.73 | ||
25 | Hs.82302 | Heparan sulfate 6-O-sulfotransferase 2, HS6ST2 | xq26.2 | 6.65 | ||
26 | Hs.132526 | Melanoma antigen, LOC51152 | 1q21.1 | 6.50 | ||
27 | Hs.2316 | SRY (sex determining region Y)-box 9, SOX9 | 17q24.3-q25.1 | 6.28 | ||
28 | Hs.166071 | Cyclin-dependent kinase 5, CDK5 | 7q36 | 6.06 | ||
29 | Hs.169300 | Transforming growth factor, beta 2, TGFB2 | 1q41 | 5.86 | ||
30 | Hs.444118 | MCM6 minichromosome maintenance deficient 6 , MCM6 | 2q21 | 5.10 | ||
31 | Hs.44532 | Ubiquitin D, UBD | 6p21.3 | 4.92 | ||
32 | Hs.105859 | Hypothetical protein FLJ10260, FLJ10260 | 17q12 | 4.59 | ||
33 | Hs.14968 | Pleiomorphic adenoma gene 1, PLAG1 | 8q12 | 4.59 | ||
34 | Hs.352213 | Hypothetical protein LOC131368, LOC131368 | 3q12.3 | 4.29 | ||
35 | Hs.445489 | Pleckstrin homology domain containing, family B member 1, PLEKHB1 | 11q13.5-q14.1 | 4.29 | ||
36 | Hs.48554 | RAP2A, member of RAS oncogene family, RAP2A | 13q34 | 3.73 | ||
37 | Hs.446698 | Basic leucine zipper transcription factor, ATF-like 2, BATF2 | 11q13.1 | 3.73 | ||
38 | Hs.44155 | Methylenetetrahydrofolate dehydrogenase 1-like, MTHFD1L | 6q25.1 | 3.56 | ||
39 | Hs.469358 | KIAA1641 | 2q11.2 | 3.48 | ||
40 | Hs.284266 | Family with sequence similarity 127, member B, FAM127B | xq26.3 | 3.48 | ||
41 | Hs.294144 | Hypothetical protein FLJ21657, FLJ21657 | 5p12 | 3.40 | ||
42 | Hs.55279 | Serine(or cysteine) proteinase inhibitor, clade B member 5, SERPINB5 | 18q21.3 | 3.36 | ||
43 | Hs.283085 | Protocadherin beta 6, PCDHB6 | 5q31 | 3.25 | ||
44 | Hs.91662 | KIAA0888 protein, KIAA0888 | 5q13.3 | 3.03 | ||
45 | Hs.171466 | Elongation factor RNA polymerase II-like 3, ELL3 | 15q15.3 | 3.03 | ||
46 | Hs.221974 | Synaptosomal-associated protein, 25 kDa, SNAP25 | 20p12-p11.2 | 2.89 | ||
47 | Hs.188662 | KIAA1702 protein, KIAA1702 | 6p11 | 2.83 | ||
48 | Hs.83450 | Laminin, alpha 3, LAMA3 | 18q11.2 | 2.60 | ||
49 | Hs.425352 | F-box protein 17, FBXO17 | 19q13.2 | 2.30 | ||
50 | Hs.390427 | Immunoglobulin kappa variable 1D-13, IGKV1D-13 | 2p12 | 2.30 | ||
51 | Hs.31442 | RecQ protein-like 4, RECQL4 | 8q24.3 | 2.14 | ||
52 | Hs.235368 | Collagen, type V, alpha 3, COL5A3 | 19p13.2 | 2.05 | ||
53 | Hs.24970 | RAB39B, member RAS oncogene family, RAB39B | xq28 | 2.00 |
引文著录: 白阳秋, 丁光伟, 杨玉秀. 肝癌发生过程中的差异基因表达. 世界华人消化杂志 2008; 16(22): 2537-2541