胃癌组织中MTA1, PTEN, E-cadherin的表达及其相互关系

表2 MTA1, PTEN, E-cadherin在胃癌组织中的表达与病理因素的关系

项目	n	MTA1		P值	PTEN		P值	E-cadherin		P值
		阴性	阳性		阴性	阳性		异常	正常
浸润深度				0.003			0.001			0.027
浆膜下	15	13(86.7%)	2(13.3%)		2(13.3%)	13(86.7%)		5(33.3%)	10(66.7%)
浸透浆膜	39	16(41%)	23(59%)		24(61.5%)	15(38.5%)		26(66.7%)	13(33.3%)
分化				0.004			0.008			0.006
高	19	14(73.7%)	5(26.3%)		7(36.8%)	12(63.2%)		6(31.6%)	13(68.4%)
中	17	11(64.7%)	6(35.3%)		5(29.4%)	12(70.6%)		10(58.8%)	7(41.2%)
低	18	4(22.2%)	14(77.8%)		14(77.8%)	4(22.2%)		15(83.3%)	3(16.7%)
淋巴转移				0.000			0.001			0.044
无	29	22(75.9%)	7(24.1%)		8(27.6%)	21(72.4%)		13(44.8%)	16(55.2%)
有	25	7(28.0%)	18(72.0%)		18(72.0%)	7(28.0%)		18(72.0%)	7(28.0%)
远隔转移				0.004			0.006			0.941
无	42	27(64.3%)	15(35.7%)		16(38.1%)	26(61.9%)		24(57.1%)	18(42.9%)
有	12	2(16.7%)	10(83.3%)		10(83.3%)	2(16.7%)		7(58.3%)	5(41.7%)
TNM分期1				0.001			0.000			0.000
Ⅰ+Ⅱ	26	20(76.9%)	6(23.1%)		6(23.1%)	20(76.9%)		8(30.8%)	18(69.2%)
Ⅲ+Ⅳ	28	9(32.1%)	19(67.9%)		20(71.4%)	8(28.6%)		23(82.1%)	5(17.9%)
性别				0.609			0.487			0.653
男	37	19(51.4%)	18(48.6%)		19(51.4%)	18(48.6%)		22(59.5%)	15(40.5%)
女	17	10(58.8%)	7(41.2%)		7(41.2%)	10(58.8%)		9(52.9%)	8(47.1%)
年龄				0.652			0.394			0.902
<60岁	24	12(50.0%)	12(50.0%)		10(41.7%)	14(58.3%)		14(58.3%)	10(41.7%)
≥60岁	30	17(56.7%)	13(43.3%)		16(53.3%)	14(46.7%)		17(56.7%)	13(43.3%)
肿瘤大小				0.507			0.099			0.297
<5 cm	37	21(56.8%)	16(43.2%)		15(40.5%)	22(59.5%)		23(62.2%)	14(37.8%)
≥5 cm	17	8(47.1%)	9(52.9%)		11(64.7%)	6(35.3%)		8(47.1%)	9(52.9%)

¹TNM分期是根据1997年国际抗癌联盟(UICC)制定的分期标准.