中药有效成分对甲基硝基亚硝基胍转化的人胃黏膜上皮细胞的毒性作用

表1 PNS, AS及Ba对GES-1细胞的抑制作用(mean±SD, %)

t/h	PNS 130 mg/L	PNS 210 mg/L	AS 90 mg/L	AS 125 mg/L	Ba 25 mg/L	Ba 40 mg/L	P+A	P+B	A+B	P+A+B
24	31.6±2.1	59.9±4.0a	32.3±6.8	57.2±4.8b	33.3±6.6	60.4±1.2c	78.6±1.6abde	61.3±1.2ac	71.1±1.2bcef	83.3±5.4abcdef
48	40.0±3.4	63.7±2.7a	39.0±2.1	72.1±3.0b	40.5±2.6	64.6±4.9c	85.6±1.0abde	72.2±2.6acdf	83.2±3.2bcef	87.9±3.6abcdef
72	41.5±1.5	75.9±0.6a	41.6±1.5	81.2±0.9b	43.7±0.7	85.8±1.1c	94.2±0.2abde	79.4±1.2acdf	92.3±0.3bcef	95.6±0.6abcdef

^aP<0.01 vs PNS 130 mg/L;

^bP<0.01 vs AS 90 mg/L;

^cP<0.01 vs Ba 25 mg/L.

^dP<0.01 vs PNS 210 mg/L;

^eP<0.01 vs AS 125 mg/L;

^fP<0.01 vs Ba 40 mg/L.