肝癌患者不同剂量化疗药物经导管动脉化疗栓塞后肝功能的变化

表2 两组TACE前后Child评分、TBIL、ALT、ALB的变化

		Child-Pugh评分	TBIL(mmol/L)	ALT (mkat/L)	ALB(g/L)
小剂量组	术前	5.8±1.1	16.9±7.4	0.96±0.85	37.0±4.8
	术后3d	7.0±1.6 b	30.3±19.3 b	3.43±2.59b	35.1±5.2 b
n= 107	术后1wk	6.2±1.4 a	24.7±15.2 b	1.97±1.68a	34.1±4.5 b
	术后4wk	6.2±1.5	17.6±9.9	1.00±0.53	36.1±4.8
	术前vs 术后3 d	t = 5.319	t = 6.707	t = 7.355	t = 2.704
	术前vs 术后1 wk	t = 2.243	t = 4.774	t = 2.568	t = 7.120
	术前vs术后4 wk	t = 1.890	t = 0.167	t = 0.396	t = 1.273
常规剂量组	术前	5.7±1.0	17.8±6.8	0.89±0.57	37.5±3.8
	术后3 d	7.3±1.6b	42.1±32.3b	2.79±2.11b	34.8±4.1b
n = 127	术后1 wk	6.7±1.2b	37.7±15.2b	1.64±0.78b	33.2±3.2b
	术后4 wk	6.6±1.4a	27.6±18.8a	1.08±0.65	33.5±3.1b
	术前vs 术后3 d	t = 8.859	t = 8.203	t = 9.820	t = 3.463
	术前vs 术后1 wk	t = 4.645	t = 6.774	t = 8.747	t = 9.798
	术前vs 术后4 wk	t = 2.603	t = 2.361	t = 1.596	t = 8.881

^aP<0.05,

^bP<0.01 vs 术前.