Effects of bowel rehabilitation and combined trophic therapy on intestinal adaptation in short bowel patients

Table 1 Patient characteristics and status

Patient No.	Gender	Age (a)	Cause of resection	Jejunum-ileum (cm)	Colon	TPN (a)	Current status	Survival time (a)
1	F	28	Small bowel volvulus	0	ACR	17	HPN	17
2	M	7	Small bowel volvulus	0	ACR	7.6	HPN	7.6
3	M	41	Small bowel volvulus	35	All	0.8	Normal oral diet	13.5
4	M	61	SMA thrombosis	30	All	1.6	Died	2.2
5	M	62	SMA thrombosis	30	All	2.0	Died	2.6
6	M	33	Small bowel volvulus	28	All	1.2	Normal oral diet	14.4
7	M	24	Small bowel volvulus	18	All	1.8	PN + EN	1.8
8	M	35	Small bowel volvulus	45	All	0.5	Died	6.2
9	F	52	Small bowel volvulus	55	ICV (-)	0.3	Died	7.4
10	F	68	SMA thrombosis	70	ICV (-)	0.6	Normal oral diet	9.5
11	F	44	Small bowel obstruction	100	All	0.2	Normal oral diet	9.6
12	M	22	Crohn’s disease	80	ICV (-)	0.5	Normal oral diet	12.2
13	M	15	Small bowel volvulus	20	ICV (-)	5.2	Died	5.4
14	M	50	Small bowel obstruction	60	ICV (-)	1.2	Normal oral diet	9.0
15	F	42	Small bowel volvulus	28	All	2.2	PN + oral diet	8.5
16	F	44	Small bowel volvulus	35	ICV (-)	1.0	Normal oral diet	10.8
17	M	59	Small bowel volvulus	30	All	1.2	Normal oral diet	6.4
18	F	50	SMA thrombosis	60	ICV (-)	0.4	Normal oral diet	5.4
19	M	55	SMA thrombosis	40	ICV (-)	1.0	Normal oral diet	7.6
20	M	56	Small bowel volvulus	30	All	0.8	PN + oral diet	4.5
21	M	26	Small bowel volvulus	30	All	1.0	Normal oral diet	8.8
22	M	40	Small bowel obstruction	50	ICV (-)	0.6	Normal oral diet	6.0
23	M	16	Small bowel volvulus	30	All	1.5	Normal oral diet	12.5
24	M	28	Small bowel volvulus	30	All	2.0	Normal oral diet	5.5
25	M	57	SMA thrombosis	45	All	0.3	Normal oral diet	6.5
26	M	34	Crohn’s disease	60	All	0.5	Normal oral diet	4.0
27	M	41	Crohn’s disease	70	All	0.4	Normal oral diet	2.0
28	M	30	Small bowel volvulus	40	All	0.2	Normal oral diet	1.8
29	M	62	SMA thrombosis	50	ICV (-)	0.8	EN + oral diet	1.6
30	F	45	Small bowel volvulus	30	All	0.5	EN + oral diet	1.5
31	M	18	Small bowel volvulus	30	All	0.4	Normal oral diet	2.0
32	M	20	Small bowel volvulus	30	All	0.5	Normal oral diet	2.0
33	M	16	Small bowel volvulus	20	All	1.0	EN + oral diet	1.5
34	M	36	Small bowel volvulus	30	All	0.4	EN + oral diet	1.2
35	M	18	Small bowel volvulus	18	All	0.6	HPN + oral diet	2.6
36	F	46	SMA thrombosis	40	ICV (-)	0.5	EN + oral diet	0.5
37	M	32	Small bowel volvulus	35	All	0.3	Normal oral diet	1.8
38	F	30	Small bowel volvulus	30	All	0.2	Normal oral diet	1.0
Mean		38 ± 16		35.8 ± 21.2		9.5 ± 6.6		5.9 ± 4.3

ACR = ascending colon resection, ICV (-) = without ileal cecal valve, HPN = home parenteral nutrition, PN = parenteral nutrition, EN = enteral nutrition,

^a = year.

Table 2 Absorption capability of patients before and after treatment with GH + GLN

	Baseline	End of therapy	One week after therapy
D-xylose test (%)	5.4 ± 2.1	7.6 ± 1.8a	6.0 ± 2.0b
15N-Gly trace test (%)	62.4 ± 14.2	73.2 ± 15.3a	58.4 ± 11.8b
13C-palmitic acid breath test (%)	55.3 ± 8.8	64.5 ± 11.2a	62.6 ± 10.4b

Values are mean ± SEM,

^aP < 0.05 vs baseline,

^bP > 0.05 vs baseline.