Liver Cancer
Copyright ©The Author(s) 2003.
World J Gastroenterol. Oct 15, 2003; 9(10): 2194-2197
Published online Oct 15, 2003. doi: 10.3748/wjg.v9.i10.2194
Table 1 General clinical data
Clinical parametersGroup A (n = 78)Group B (n = 176)
Age (yr)51.72 (36-71)49.66 (14-74)
Male69 (88.64%)147 (83.52%)
HbsAg (+)67 (85.89%)151 (85.79%)
Child-Push grade
Grade A41 (52.54%)a124 (70.45%)
Grade B28 (35.90%)a38 (21.59%)
Grade C9 (11.53%)14 (8.0%)
Total resection rate47.92% (254/530)a33.21% (176/530)
Procedure time (min)268 (150-325)a178 (128-356)
Blood exclusion time (min)25.4 (12-55)a14.2 (8-28)
Blood loss (mL)818 (250-2800)725 (180-2400)
Blood transfusion (mL)690 (0-2400)620 (0-2600)
Total hospital stay time (d)29.4 (12-35)19.8 (10-39)
Re-operation11 (14.10%)16 (9.09%)
Emergency operation5 (6.41%)9 (5.11%)
Local hepatectomy12 (15.38%)a48 (27.28%)
Minor hepatectomy21 (26.92%)a96 (54.55%)
Major hepatectomy45 (57.69%)a32 (18.19%)
Caudate lobe hepatectomy4 (5.13%)a0 (0)
Table 2 Pathologic data
Clinical parametersGroup A (n = 78)Group B (n = 176)
The mass
Median diameter (cm)11.58 (6.2-24.6)a6.25 (1.8-12.7)
> or = 5 cm72 (92.30%)a118 (67.05%)
> or = 10 cm53 (67.95%)a28 (15.90%)
Close or invade vana cana23 (29.49%)a17 (9.65%)
Close or invade major21 (26.92%)a13 (7.39%)
hepatic vein
Close or invade major bile duct11 (14.10%)a8 (4.55%)
Close or invade major port vein32 (41.03%)a22 (12.5%)
TNM tumor stage
Stage 16 (7.69%)a49 (27.84%)
Stage 212 (15.38%)a71 (40.34%)
Stage 336 (46.15%)a32 (18.19%)
Stage 4a20 (25.64%)a22 (12.5%)
Stage 4b4 (5.13%)a2 (1.14%)
Cirrhosis59 (75.64%)120 (68.18%)
Multiple tumor8 (10.25%)a6 (3.41%)
Caudate lobe tumor4 (5.13%)a0 (0)
Tumor free resection margin74 (94.87%)173 (98.3%)
Tumor rupture during operation11 (14.10%)a13 (7.39%)
Table 3 Postoperative complications
Clinical parametersGroup AGroup B
Bleeding16 (20.51%)29 (16.48%)
Bile leakage6 (7.69%)a8 (4.55%)
Infection (including abscess)12 (15.38%)23 (13.68)
Pleural effusion31 (39.74%)a34 (19.32%)
Reoperation within 24 h3 (3.85%)6 (3.40%)
after operation
Ascites16 (20.51%)a20 (11.36%)
Jaundice6 (7.69%)a5 (2.84%)
Hepatic failure6 (7.69%)a5 (2.84%)
Total morbidity40 (51.28%)a45 (25.57%)
Perioperative mortality2 (2.56%)5 (2.84%)
Table 4 Outcome after hepatic resection
Clinical parametersGroup AGroup BGroup C
Median disease-free14.6 (8-25)16.3 (9-37)-
survival (m)
Median survival (m)40.5 (28-52)57.6 (33-84)8.8 (5-31)
Cumulative survival rate
1 year survival92.3%b95.5%b29.9%
3 year survival51.3%ab69.6%b2.9%
5 year survival34.6%ab48.0%b0
Remote metastasis rate16.27%a23.9%b14.8%