Relationship between autoimmune hepatitis and HLA-DR4 and DRβ allelic sequences in the third hypervariable region in Chinese

Table 1 Allelic frequencies of DRB1 in autoimmune hepatitis

DRB1 allele	DR Ag	Autoimmune hepatitis % (n = 32)	Healthy control % (n = 48)	RR	P value	Corrected P value
DRB1*01	DR1	0.0	4.2
DRB1*15, *16	DR2	37.5	35.4
DRB1*03	DR3	15.6	14.6
DRB1 *04	DR4	46.9	20.8	3.35	0.014	0.026
DRB1*11, *12	DR5	12.5	29.2
DRB1*13, *14	DR6	9.4	12.5
DRB1*07	DR7	3.1	4.2
DRB1*08	DR8	9.4	10.4
DRB1*09	DR9	34.4	37.5
DRB1*10	DR10	0	2.1

P values are given only where significant at ＜ 0.05 level.

Table 2 Allelic frequencies of DRB1 *04 subtypes in autoimmune hepatitis

Allele	Autoimmune hepatitis % (n = 32)	Healthy control % (n = 48)	RR	P value	Corrected P value
DR4	46.9 (15)	20.8 (10)	3.4	0.014	0.026
DRB1 *0401	3.1 (1)	4.2 (2)
DRB1 *0402	0	0
DRB1 *0403	3.1 (1)	4.2 (2)
DRB1 *0404	12.5 (4)	2.1 (1)
DRB1 *0405	21.9 (7)	6.3 (3)	4.2	0.04	0.08
DRB1 *0406	3.1 (1)	4.2 (2)
DRB1 *0407	0	0
DRB1 *0408	0	0
DRB1 *0409	0	0
DRB1 *0410	6.2 (2)	0
DRB1 *0411	0	0

P values are given only where significant at ＜ 0.05 level.