First prospective European study for the feasibility and safety of magnetically controlled capsule endoscopy in gastric mucosal abnormalities

Table 1 Indications of small bowel capsule endoscopy (grouped by gender)

	All cases	Male	Female
Patient characteristics
n	284	149	135
Age (mean ± SD)	44.0 ± 13.3	44.0 ± 13.3	44.0 ± 13.3
BMI	26.5	27.1	25.5
Indications
OGiV	61 (21.5%)	30 (20.1%)	31 (22.9%)
Celiac disease	80 (28.2%)	40 (26.8%)	40 (29.7%)
Crohn’s or susp. Crohn’s	47 (16.5%)	31 (20.9%)	16 (11.9%)
Unexplained abdominal pain	92 (32.4%)	47 (31.5%)	45 (33.3%)
Susp. SB tumor	4 (1.4%)	1 (0.7%)	3 (2.2%)
13C urea breath test
No. of performed tests	110(38.7%)	56 (50.1%)	54 (49.1%)
Positive	36 (32.7%)	16 (44.4%)	20 (55.6%)
Negative	74 (67.3%)	40 (54%)	34 (46%)

BMI: Body mass index; SB: Small bowel.

Table 2 The results of Helicobacter pylori C13 urea breath tests

	n	H. pylori positive	%	H. pylori negative	%	χ2	P value
Normal	30	7	23%	23	77%	0.9775	0.3228	NS
Minor proximalgastritis	19	9	47%	10	53%	1.529	0.2163	NS
Minor antralgastritis	19	4	21%	15	79%	1.0322	0.3096	NS
Active, erosive antralgastritis	15	6	40%	9	60%	0.3129	0.5759	NS
Proximal erosivegastritis	22	7	32%	15	68%	0.0069	0.9338	NS
Pangastritis (proximal and antral)	4	3	75%	1	25%	0.5	0.4795	NS
Total HP tested patients	110	36	33%	74	67%	-	-	-

H. pylori: Helicobacter pylori.

Table 3 Mean gastric, small bowel, and overall transit times of magnetically controlled capsule endoscopy

Transit time	All cases	SD	Male	Female
Stomach	0 h 47 min 40 s	0 h 43 min 29 s	0 h 44 min 15 s	0 h 51 min 14 s
Small bowel	3 h 46 min 22 s	2 h 1 min 24 s	3 h 52 min 46 s	3 h 38 min 21 s
Total	5 h 48 min 35 s	1 h 50 min 49 s	5 h 46 min 37 s	5 h 50 min 18 s

Table 4 Diagnostic yield of magnetically controlled capsule endoscopy

Diagnostic yield	Major	Minor	Total
Total	38 (13.3%)	195 (68.6%)	233 (81.9%)
Gastric	14 (4.9%)	159 (55.9%)	173 (60.8%)
SB	24 (8.4%)	36 (12.7%)	60 (21.1%)

SB: Small bowel.

Table 5 Distribution of pathologies detected by magnetically controlled capsule endoscopy

	Polyp ventriculi	Ulcus ventriculi	Coeliakia	Crohn	Gastritis	Small intestinal diverticula	Angiodysplasia	Aspecific infalmmation in small bowel
Major pathologies	5	9	1	23	159	1	26	9

Table 6 Distribution of different types of transpyloric transit in complete and incomplete small bowel studies

	Cases (n)	Mean total transit time	Mean gastric transit time	Mean SB transit time	Transpyloric transit
					With magnet by automatic protocol	With magnet manually	Without magnet
Total study population	284	5 h 48 min 35 s	0 h 47 min 40 s	3 h 46 min 22 s	56 (19.7%)	63 (22.2%)	165 (58.1%)
Incomplete studies	18 (6.3%)	7 h 13 min 41 s	0 h 52 min 35 s	6 h 19 min 51 s	2	5	11
The capsule depleted (> 5 h)	10 (3.5%)	9 h 12 min 9 s	0 h 46 min 5 s	8 h 26 min 4 s	0	3	7
The capsule depleted (< 5 h)	3 (1%)	2 h 23 min 25 s	0 h 24 min 9 s	1 h 51 min 22 s	1	0	2
The patient requested to terminate	3 (1%)	4 h 45 min 9 s	0 h 50 min 3 s	3 h 55 min 6 s	1	1	1
The capsule stopped because of a disease	2 (0.7%)	8 h 19 min 36 s	2 h 11 min 33 s	6 h 8 min 33 s	0	1	1

SB: Small bowel.