Metal stents placement for refractory pancreatic duct stricture in children

Table 1 Baseline characteristics of the 8 patients with refractory benign dominant main pancreatic duct strictures treated with a fully covered self-expandable metal stent

Case no.	Sex	Anatomical abnormality	Genetic mutation	No. of previous plastic1 stent placements	Placement time for each plastic stent (d), median (range)	Age at first insertion of a FCSEMS (yr)	Location of the stricture	Diameter and length of the stent (mm/cm)
1	F	Pancreas divisum	PRSS1	2	25.5 (19-32)	17	Head	6/4
2	M	-	SPINK1	7	42.0 (4-93)	12	Head	6/5
3	M	Incomplete pancreas divisum	-	4	126.5 (63-431)	10	Head	6/6
4	M	Pancreas divisum	CFTR	3	57.0 (1-109)	12	Body	6/7
5	F	-	PRSS1	1	46.0	18	Neck	6/7
6	M	-	PRSS1	2	58 (24-92)	5	Head	6/4
7	F	-	SPINK1	1	87	9	Head	6/4
8	M	-	SPINK1	1	29	16	Neck	6/7

¹Single and multiple stents were used in our study. FCSEMS: Fully covered self-expandable metal stent.

Table 2 Resolution of pancreatic duct strictures after the first placement of a fully covered self-expandable metal stent

Case no.	Duration of stenting (mo)	Diameter of the stricture (cm)		Diameter of the dilated segment1 (cm)
		Pre	Post	Pre	Post
1	3	0.8	3.0	6.5	4.9
2	10	1.5	2.0	12.1	8.7
3	6	1.2	3.4	11.3	7.1
4	6	0.9	3.4	8.1	6.4
5	6	1.0	4.4	7.1	5.0
6	6	0.9	0.9	6.0	5.2
7	6	1.6	2.1	9.4	6.1
8	6	0.8	3.0	7.0	7.0
mean ± SD	62	1.1 ± 0.3	2.8 ± 0.9	8.4 ± 2.5	6.3 ± 1.6
P value	NA	0.017		0.018

¹The diameter was measured at the dilated segment upstream of the pancreatic duct stricture;

²Expressed as a median value. NA: Not applicable.

Table 3 Feasibility and safety of the placement of a fully covered self-expandable metal stent based on the occurrence of adverse events

Case no.	Stent migration	Stent patency	Pancreatitis	Cholestasis	Bowel perforation	Sepsis	Mortality
1	N	Y	N	N	N	N	N
2	N	Y	N	N	N	N	N
3	N	Y	N	N	N	N	N
4	N	Y	N	N	N	N	N
5	N	Y	N	N	N	N	N
6	N	Y	N	N	N	N	N
7	N	Y	N	N	N	N	N
8	N	Y	N	N	N	N	N

N: No; Y: Yes.