Esophageal Helicobacter pylori colonization aggravates esophageal injury caused by reflux

Table 1 Incidence of Barrett’s esophagus and esophageal adenocarcinoma in rats n (%)

Groups (n)		BE	EAC
I	Pseudo-operation (8)	0	0
II	Pseudo-operation with H. pylori infection (8)	0	0
III	EGDA (9)	3 (33.3)	1 (11.1)
IV	EGDA with H. pylori infection
	Concomitant esophageal colonization (10)	8 (80.0)a	6 (60.0)ac
	Only gastric colonization (9)	2 (22.2)	1 (11.1)

^aP < 0.05 vs pseudo-operation and pseudo-operation with Helicobacter pylori (H. pylori) infection groups;

^cP < 0.05 vs esophagogastroduodenal anastomosis (EGDA) group. BE: Barrett’s esophagus; EAC: Esophageal adenocarcinoma.