Pouch size influences clinical outcome of pouch construction after total gastrectomy: A meta-analysis

Table 1 Characteristics of included studies

Study	Reconstruction	Study period	Group	Pouch size (cm)	Cases	Age (yr)	Gender (M/F)	Tumor stage	Follow-up (yr)
Tsujimoto et al[6]	Double-tract	2002-2007	Small pouch	9.2 ± 1.1	13	54.6 ± 10.0	7/6	IA IB II IIIA	5.0
			Large pouch	12.5 ± 1.5	14	61.7 ± 8.2	12/2	4 3  3 3
								6 1  3 4
Hoksch et al[8]	Pouch-JI	1995-1999	Small pouch	7	15	52 (25-72)	6/9	0 IA IB II IIIA IIIB IV	1.0
			Large pouch	15	13	61 (51-74)	6/7	0 2 2 8 2 1 0
								1 2 5 3 1 1 0
Tanaka et al[9]	Double-tract	1992-1995	Small pouch	15	12	57.2 ± 11.09	7/5	I II III IV	1.0
			Large pouch	20	9	62.1 ± 9.44	6/3	4 3 5 0
								4 1 4 0
Tanaka et al[10]	Double-tract	1992-1994	Small pouch	15	9	56.4 ± 15	3/6	I II III IV	1.0
			Large pouch	20	9	62.1 ± 9.44	6/3	2 3 4 0
								4 1 4 0
Schwarz et al[11]	Pouch-JI	1990-1993	Small pouch	10	12	59 ± 3.1	9/3	I + II III + IV	0.5
			Large pouch	20	12	62 ± 3.59	4/8	6 6
								8 4
Schwarz et al[11]	Pouch-RY	1990-1993	Small pouch	10	12	63 ± 3.47	9/3	I + II III + IV	0.5
			Large pouch	20	12	65 ± 3.74	4/8	5 7
								4 8

JI: Jejunal interposition reconstruction; RY: Roux-en-Y reconstruction.

Table 2 Main results of included studies

Study	Group	Cases	Morbidity	Mortality	OP time (min)	Heartburn incidence		Dysphagia		Vomiting		Daily meals (n)					Eating capacity per meal		Body weight				Quality of life
Tsujimoto et al[6]	Small pouch	13	2/13	0	331.8 ± 34.4	1 yr	2 yr	1 yr	2 yr	1 yr	2 yr	1 yr			2 yr		1 yr	2 yr					NR
						2/11	0	7/11	0	1/11	0	3 time	4 time	5 time	3 time	4 time
	Large pouch	14	2/14	0	343.8 ± 36.7	4/13	0	8/13	1/13	3/13	1/13	10/11	9/13	0	10/11	1/11	69.1% ± 19.7%	78.6% ± 6.9%	88.4% ± 7.4%		90.2% ± 6.4%		NR
												9/13	3/13	1/13	8/13	5/13	52.3% ± 16.9%	61.4% ± 23.4%	85.9% ± 4.3%		80.9% ± 7.1%
Hoksch et al[8]	Small pouch	15	NR	NR	NR	NR		NR		NR		Pre	14 d	3 mo	6 mo	1 yr	NR		14 d	3 mo	6 mo	1 yr	EORTC QLQ-C30
	Large pouch	13	NR	NR	NR	NR		NR		NR		4.8 ± 0.2	6.2 ± 0.1	6.1 ± 0.2	5.2 ± 0.2	4.8 ± 0.2	NR		95% ± 0.6%	90% ± 1.0%	87% ± 0.8%	87% ± 1.2%
												4.5 ± 0.1	6.6 ± 0.2	6.4 ± 0.1	5.0 ± 0.1	4.3 ± 0.1			95% ± 0.4%	86% ± 0.8%	86% ± 0.8%	92% ± 1.1%
Tanaka et al[9]	Small pouch	12	NR	NR	NR	NR		NR		NR		NR					3 mo	1 yr	3 mo		1 yr		NR
	Large pouch	9	NR	NR	NR	NR		NR		NR		NR					55.2% ± 25%	59.1% ± 8.6%	57.05% ± 4.73%		85.5% ± 4.2%		NR
																	40.6% ± 9%	49.6% ± 16.5%	67.73% ± 10.11%		87.3% ± 6.9%
Tanaka et al[10]	Small pouch	9	NR	NR	NR	1 yr		1 yr		1 yr		NR					NR		NR				NR
						1/9		6/9		2/9
	Large pouch	9	NR	NR	NR	5/9		8/9		4/9		NR					NR		NR				NR
Schwarz et al[11]	Small pouch	12	NR	NR	335 ± 9.79	NR		NR		NR		NR					NR		Absolute weights				UC
	Large pouch	12	NR	NR	374 ± 11.1	NR		NR		NR		NR					NR
Schwarz et al[11]	Small pouch	12	NR	NR	295 ± 7.51	NR		NR		NR		NR					NR		Absolute weights				UC
	Large pouch	12	NR	NR	360 ± 8.6	NR		NR		NR		NR					NR

NR: Not reported; UC: Unclear.