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Copyright ©2010 Baishideng.
World J Gastroenterol. Aug 14, 2010; 16(30): 3804-3810
Published online Aug 14, 2010. doi: 10.3748/wjg.v16.i30.3804
Table 1 Meta-analysis comparing transthoracic and transhiatal esophagectomy
Meta-analysisRindani et al[20]Hulscher et al[21]
No. of patients54837527
Postoperative mortality (%)
TT9.59.2
TH6.35.7
Intraoperative blood loss (mL)
TT11711001
TH1311728
Hospital stay (d)
TT19.821
TH19.517.8
Pulmonary complications (%)
TT2518.7
TH2412.7
Cardiac complications (%)
TT10.56.6
TH12.419.5
Anastomotic leakage (%)
TT107.2
TH1613.6
Vocal cord paralysis (%)
TT4.83.5
TH11.29.5
5-yr OS (%)
TT2623
TH2421.7
Table 2 Randomized trials comparing transthoracic and transhiatal esophagectomy
Meta-analysisGoldminc et al[27]Chu et al[28]Jacobi et al[29]Hulscher et al[30,31]
No. of patients673932220
Postoperative mortality (%)
TT8.6064
TH6.2062
Intraoperative blood loss (mL)
TT1(2.3 units transfused)67122701900
TH1(2.3 units transfused)72410001000
Hospital stay (d)
TT18272119
TH20.5182315
Postoperative pneumonia (%)
TT2003157 (atelectasis included)
TH19101927 (atelectasis included)
Cardiac complications (%)
TT115.81926
TH1153116
Anastomotic leakage (%)
TT9012.516 (subclinical included)
TH6012.514 (subclinical included)
Vocal cord paralysis (%)
TT31121 (transient)
TH31113 (transient)
Reported survival (%)
TT22 at 3 yrMedian survival 13.5 mo77 at 1 yr36 at 5 yr
TH30 at 3 yrMedian survival 16 mo70 at 1 yr34 at 5 yr