Adenovirus-mediated CTLA4Ig gene inhibits infiltration of immune cells and cell apoptosis in rats after liver transplantation

Table 1 Comparison in the infiltration of macrophage and CD8-positive cells in portal area (mean±SD).

Group	Post-operative time (d)
	1	3	5	7	12
Macrophage
Group I	2.11±1.54	20.13±8.34	106.75±22.56	49.82±14.74	29.22±8.69
Group II	2.42±1.68	10.78±3.70a	29.64±10.60b	33.25±12.44b	21.78±7.17a
Group III	1.90±1.45	3.50±2.37bd	5.31±2.66bd	2.45±2.50bd	2.90±2.38bd
CD8-positive cells
Group I	1.25±1.04	57.43±19.64	87.29±23.44	130.83±31.61	60.67±19.71
Group II	2.13±1.64	5.11±3.02b	14.88±7.02b	8.79±6.65b	28.86±8.03b
Group III	1.22±1.48	5.60±2.55b	6.00±2.31bc	2.18±1.83bd	3.22±2.91bd

^aP<0.05,

^bP<0.01 vs Group I;

^cP<0.05,

^dP<0.01 Group II vs Group III.

Table 2 Comparison apoptosis index after transplantation (mean±SD).

Group	Post-operative time (d)
	1	3	5	7	12
Group I	2.70±2.50	14.30±11.61	22.10±7.59	14.50±12.80	11.30±10.71
Group II	2.60±3.78	2.00±1.63b	2.80±1.87b	4.90±5.57b	6.50±6.93
Group III	2.30±2.58	2.10±1.79b	3.20±2.66b	2.40±1.96b	3.90±4.23a

^aP<0.05,

^bP<0.01 vs GroupI.

Table 3 Comparison in rejection grade after transplantation (mean±SD).

Group	Post-operative time (d)
	1	3	5	7	12
Group I	0,0,0	2,1-2,2	3,2-3,2-3	3,2-3,3	3,3,2-3
Group II	0,0,0	0,0,0a	0-1,0-1,1a	1,0-1,1a	1,1,1-2a
Group III	0,0,0	0,0-1,0a	0,0-1,0a	0,1,0-1a	0,0,1ab

^aP<0.05, vs Group;

^bP<0.01 Group II vs Group III.