Effects of glucocorticoids on the growth and chemosensitivity of carcinoma cells are heterogeneous and require high concentration of functional glucocorticoid receptors

Table 1 Correlation of GR content with the effect of DEX in carcinoma cells

Cells	Origin	Effect of DEX	GR (sites/cell)
MCF7	Breast	Growth inhibition	6.37×104
MCF7/TPT300	Breast	Growth inhibition	7.43×104
MCF7/MXR1	Breast	Growth inhibition	5.9×104
HeLa	Uterine cervix	Growth inhibition	1.94×104
SiHa	Uterine cervix	Increased sensitivity toward cisplatin	8.1×104
H460	Lung	Increased resistance toward cisplatin	2.1×104
Hep3B	Liver	Increased resistance toward cisplatin	4.3×104
NPC-TW01	Nasopharyngeal	No effect	4.2×104
NPC-TW04	Nasopharyngeal	No effect	2.0×104
Caski	Uterine cervix	No effect	7.2×103
Huh 7	Liver	No effect	7.9×103
AGS	Stomach	No effect	5.7×103
N87	Stomach	No effect	5.0×103
SNU1	Stomach	No effect	1.97×103

DEX: dexamethasone; GR: glucocorticoid receptor.