Viral Hepatitis
Copyright ©The Author(s) 2005.
World J Gastroenterol. Sep 28, 2005; 11(36): 5666-5671
Published online Sep 28, 2005. doi: 10.3748/wjg.v11.i36.5666
Table 1 Binding protein of C12 protein screened by yeast two-hybrid
Homeobox geneHomogeneity %Clones
Cathepsin B991
Apolipoprotein M981
Cytochrome C oxidase II97–993
Receptor JAK (EPHB4) variation factor991
KH splicing regulation protein (KSRP)981
Phosphatidylinositol deacylase971
poly-glucose Q transcriptional variation factor 1
Ferritin light chain992
Ornithine decarboxylase 1991
Metallothionein 2A98–1003
Blood coagulation factor IX1001
Acetolactate synthase991
Calpain981
Exo-nucleus triphosphate diplo-phosphoinostide991
hydrolase 5
Plasma globulin inhibitive factor H4991
Novel gene1002
Table 2 Differential expression genes upregulated by C12 gene
GenBank numberHomeobox gene
208Insulin receptor (INSR),
5500SUMO-1 activating enzyme subunit 1 (SAE1),
6292Tumor susceptibility gene 101 (TSG101),
12248Selenophosphate synthetase 2 (SPS2),
6217Serine (or cysteine) proteinase inhibitor, clade I
(neuroserpin), member 2 (SERPINI2),
16614TRAF and TNF receptor-associated protein (TTRAP),
6437ADP-ribosyltransferase-like 1 (ADPRTL1)
33306Caspase 4, apoptosis-related cysteine protease
(CASP4), transcript variant gamma,
L04731Translocation T (4:11) of ALL-1 gene
2085Glutathione peroxidase 4 (phospholipid
hydroperoxidase) (GPX4),
4728DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide
21 (DDX21),
2624Prefoldin 5 (PFDN5), transcript variant 1,
6415Serine palmitoyl transferase, long chain base
subunit 1 (SPTLC1),
4127G protein pathway suppressor 1 (GPS1),
14887Hypothetical protein from BCRA2 region
660Transforming growth factor, beta 1 (TGF-β 1),