Effect of early nutrition on intestine development of intrauterine growth retardation in rats and its correlation to leptin

Table 1 Content ratio of different components (g) in 100 g food

Components	Protein	Fat	Carbohydrate	Total energy (kJ/100 g)
Normal diet	22.5	3.9	57.8	1 583.4
High protein diet	28.6	3.9	56.8	1 625.4
Low protein diet	11.3	8.5	58.7	1 558.2
χ2	10.09	3.04	0.09	–
P	0.006a	0.22	0.96	–

^aP<0.05 vs other.

Table 2 Leptin, BW, BL, IW, IL, and disaccharidase activities in all groups (mean±SD) n = 8/group

Age (yr)	Group	Leptin (ng/mL)	BW (g)	BL (cm)	IW (g)	IL (cm)	Lactase	Saccharase	Maltase
0 wk	C	ND	6.01 ± 0.55	6.26 ± 0.44	0.10 ± 0.02	21.8 ± 2.7	315 ± 19	13 ± 6	58 ± 20
	SC	ND	4.50 ± 0.41a	5.96 ± 0.40a	0.05 ± 0.01a	15.9 ± 2.8a	383 ± 39a	15 ± 8	269 ± 17a
4th wk	C	0.26 ± 0.08	60.8 ± 9.5	23.1 ± 1.4	2.2 ± 0.2	74.8 ± 9.1	54 ± 15	258 ± 27	751 ± 102
	SC	0.36 ± 0.20	52.0 ± 10.9a	21.0 ± 2.5a	1.4 ± 0.3a	70.3 ± 3.4	39 ± 14	254 ± 23	797 ± 95
	SH	0.21 ± 0.03c	70.0 ± 4.5c	23.6 ± 0.5c	1.9 ± 0.2	80.7 ± 9.5	62 ± 8	230 ± 21	368 ± 26ac
	SL	0.58 ± 0.12ac	21.4 ± 3.5ac	16.0 ± 1.3ac	0.8 ± 0.4ac	53.9 ± 3.1ac	66 ± 22	138 ± 32ac	344 ± 33ac
12th wk	C	0.40 ± 0.23	235.5 ± 43.4	38.5 ± 0.8	4.3 ± 0.7	122.7 ± 12.6	48 ± 3	230 ± 32	713 ± 158
	SC	0.79 ± 0.41a	208.6 ± 21.6	36.9 ± 1.7	3.9 ± 0.9	101.2 ± 5.8a	50 ± 21	262 ± 43	670 ± 157
	SH	0.42 ± 0.15c	254.8 ± 23.5ac	37.1 ± 0.4	4.1 ± 0.4	122.3 ± 13.0	48 ± 12	242 ± 27	682 ± 144
	SL	0.38 ± 0.25c	169.3 ± 6.7ac	33.2 ± 0.8ac	3.3 ± 0.6a	99.6 ± 6.9a	53 ± 12	239 ± 35	568 ± 52

Disaccharidase activity unit: mmol/(min·g) protein.

^aP<0.05, IUGR group vs C group;

^cP<0.05, SL, and SH groups vs SC group. ND: not determined.