Expression of gamma-aminobutyric acid A receptor subunits &alpha;1, &beta;1, &gamma;2 mRNA in rats with hepatic encephalopathy

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Jun 7, 2005 (publication date) through May 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 7, 2005; 11(21): 3319-3322
Published online Jun 7, 2005. doi: 10.3748/wjg.v11.i21.3319

Table 1 Gray values of mRNA expression levels of GABA_A receptor subunits α₁, β₁, γ₂ in rats with hepatic encephalopathy (mean ± SD).

Position	α₁ mRNA		β₁ mRNA		γ₂ mRNA
Position	Control group	HE model	Control group	HE model	Control group	HE model
Basal nuclei	184.14±4.41	144.7±15.67^b	182.80±5.20	141.62±15.09^b	167.97±16.23	136.81±26.41^b
Cerebral cortex	149.54±13.74	154.9±11.02	141.96±17.55	155.26±10.24	142.47±15.69	143.29±24.87
Substantia nigra pars reticularis	113.07±32.44	60.61±33.66^b	134.21±43.76	69.13±30.74^b	113.18±36.52	51.00±36.14^b
Substantia nigra pars compacta	128.40±18.85	87.71±21.25^b	151.01±19.49	87.87±25.16^b	126.90±19.74	86.35±20.30^b
Hippocampal CA1	161.60±4.56	122.34±5.56^b	162.33±3.92	122.14±6.30^b	178.62±6.45	162.15±9.05^a
Hippocampal CA2	140.65±4.15	123.29±5.21^b	137.19±7.12	122.81±5.09^b	162.70±5.90	161.57±6.40
Hippocampal CA3	140.09±4.52	123.40±4.42^b	138.11±5.92	123.00±4.63^b	162.09±5.35	161.36±5.04
Hippocampal CA4	140.09±4.12	124.76±4.18^b	138.81±6.10	125.75±2.43^b	158.97±6.12	160.1±5.21

^aP<0.05,

^bP<0.01 vs control group HE: hepatic encephalopathy.

Citation: Li XQ, Dong L, Liu ZH, Luo JY. Expression of gamma-aminobutyric acid A receptor subunits α₁, β₁, γ₂ mRNA in rats with hepatic encephalopathy. World J Gastroenterol 2005; 11(21): 3319-3322
URL: https://www.wjgnet.com/1007-9327/full/v11/i21/3319.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i21.3319