Liver Cancer
Copyright ©The Author(s) 2004.
World J Gastroenterol. Mar 1, 2004; 10(5): 643-648
Published online Mar 1, 2004. doi: 10.3748/wjg.v10.i5.643
Table 1 Demographic, clinical and tumor variables of patients with HCC undergoing curative resection (n = 50)
VariablesNo. of patients (%)
Age (mean, years)56.2 ± 13
Male31 (62)
Child- Pugh’s class A43 (86)
Serum AFP < 20 ng/mL16 (32)
20-103 ng/mL18 (36)
> 103 ng/mL14 (28)
HBsAg (+)36 (72)
Anti-HCV (+)13 (26)
Size of HCC < 3 cm12 (24)
3-10 cm13 (26)
> 10 cm25 (50)
Cirrhosis40 (80)
Edmondson-Steiner’s Grade I4 (8)
Grade II12 (24)
Grade III18 (36)
Grade IV16 (32)
Complete capsule19 (38)
Vascular permeation29 (58)
Daughter nodules31 (62)
Tumor necrosis33 (66)
Tumor hemorrhage29 (58)
Table 2 Predictors of HCC recurrence
VariableP values
UVMV
Sex0.895-
Age0.279-
Size(< 3 cm, > 10 cm)0.415-
Liver cirrhosis0.510-
Child-Pugh class0.528-
Serum AFP0.744-
HBsAg (+)0.280-
Anti-HCV (+)0.481-
Edmondson Steiner grade0.00050.033
Capsule< 0.00010.020
Vascular permeation< 0.00010.018
Daughter nodules< 0.00010.006
Tumor necrosis0.344-
Tumor hemorrhage0.812-
Serum VEGF165 mRNA0.02060.050
Serum VEGF121 mRNA0.520-
Table 3 Correlation between clinical and tumor variables and recurrence-related mortality
VariablesP values
UVMV
Sex0.510-
Age0.440-
Size (<3 cm, > 10 cm)0.519-
Liver cirrhosis0.510-
Child-Pugh class0.548
HBsAg (+)0.351-
Anti-HCV (+)0.521-
Edmondson Steiner grade< 0.0010.053
Capsule0.033n.s.
Vascular permeation< 0.0010.045
Daughter nodules0.016n.s.
Tumor necrosis0.373-
Tumor hemorrhage0.306-
Serum VEGF165 mRNA< 0.0010.048
Serum VEGF121 mRNA0.763-