Abnormal immunity and gene mutation in patients with severe hepatitis-B

Table 1 Status of T subgroups in the peripheral blood from patients with severe hepatitis (%, ^-x±s)

Group	n	CD3+	CD4+	CD8+	CD4+/CD8+
Control	20	0.60 ± 0.17	0.46 ± 0.05	0.33 ± 0.03	1.39 ± 0.18
AH	22	0.61 ± 0.06	0.38 ± 0.04a	0.33 ± 0.04	1.16 ± 0.20
FH	23	0.53 ± 0.07a	0.37 ± 0.03a	0.25 ± 0.06a	1.63 ± 0.30a
Mutation	12	0.15 ± 0.08	0.37 ± 0.12	0.16 ± 0.02b	2.35 ± 0.89b
Wild	11	0.56 ± 0.04	0.36 ± 0.04	0.28 ± 0.05	1.31 ± 0.18

^aP < 0.01 vs control;

^bP < 0.05 vs wild type. AH: Acute hepatitis, FH: Severe hepatitis.