S-phase delay in human hepatocellular carcinoma cells induced by overexpression of integrin β1

Figure 7 Effects of laminin on transfected cells. Protein levels of phosphorylated FAK (A) and Ser473-phosphorylated form of PKB (B) were increased in the transfected cells, especially in β1-7721 and α5β1-7721 cells grown in the LN-coated culture dishes for 60 minutes. (C) Under the same condition, p27^kip1 protein level was decreased in β1-7721 and α5β1-7721 cells. Lane 1, mock cells; lane 2, α5-7721; lane 3, β1-7721; lane 4, α5β1-7721. Each result represented at least 3 independent experiments.