Characterization of focal hepatic lesions with contrast-enhanced C-cube gray scale ultrasonography

Figure 3 A 62-year-old woman with cholangiocarcinoma. A. Subcostal section of precontrast conventional sonography shows a hypoechogenic lesion (arrows) in segment V of the liver with a diameter of 8.0 cm. B-E. Contrast-enhanced C-cube gray scale sonography at 16 s (B), 20 s (C) and 25 s (D) after injection of Levovist shows that intranodular signals enhance gradually and earlier than the liver parenchyma, and enhancement decreases rapidly in the portal venous phase (78 s, E). Histopathology of US-guided percutaneous biopsy reveals cholangiocarcinoma of the liver.