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©The Author(s) 2003.
World J Gastroenterol. Aug 15, 2003; 9(8): 1662-1666
Published online Aug 15, 2003. doi: 10.3748/wjg.v9.i8.1662
Published online Aug 15, 2003. doi: 10.3748/wjg.v9.i8.1662
Table 2 Relationship between expression of PTEN in primary foci and clinicopathological features of gastric cancer
Clinicopathological features | n | PTEN expression | rs | P value | ||||
- | + | ++ | +++ | PR(%) | ||||
Tumor size | 0.045 | 0.639 | ||||||
< 4 cm | 47 | 20 | 6 | 4 | 17 | 57.4 | ||
≥ 4 cm | 66 | 31 | 7 | 7 | 21 | 53.0 | ||
Borrmann’s Classification | 0.070 | 0.544 | ||||||
I/II | 28 | 12 | 3 | 3 | 10 | 57.1 | ||
III/IV | 59 | 30 | 5 | 6 | 18 | 49.2 | ||
Invasive depth | 0.274 | 0.003 | ||||||
Above submucosa | 26 | 7 | 4 | 2 | 13 | 73.1 | ||
Muscularis propria | 34 | 14 | 2 | 4 | 14 | 58.8 | ||
Below subserosa | 53 | 30 | 7 | 5 | 11 | 56.6 | ||
Metastasis | 0.197 | 0.036 | ||||||
Negative | 76 | 28 | 10 | 8 | 29 | 62.7 | ||
Positive | 38 | 23 | 3 | 3 | 9 | 39.5 | ||
TNM staging | 0.129 | 0.172 | ||||||
O | 18 | 7 | 4 | 1 | 6 | 61.1 | ||
I | 28 | 11 | 2 | 2 | 13 | 60.7 | ||
II | 40 | 19 | 3 | 5 | 13 | 52.5 | ||
III | 17 | 7 | 3 | 3 | 4 | 58.8 | ||
IV | 10 | 7 | 1 | 0 | 2 | 30.0 | ||
Growth pattern | 0.282 | 0.008 | ||||||
Mass | 23 | 8 | 2 | 2 | 11 | 65.2 | ||
Nest | 30 | 12 | 3 | 4 | 11 | 60.0 | ||
Diffuse | 34 | 22 | 3 | 3 | 6 | 35.3 | ||
Lauren’s Classification | 0.345 | 0.000 | ||||||
Intestinal type | 36 | 8 | 2 | 6 | 20 | 77.8 | ||
Diffuse type | 57 | 32 | 10 | 3 | 12 | 43.9 | ||
Mixed type | 20 | 11 | 1 | 2 | 6 | 45.0 | ||
Histological classification | 0.262 | 0.005 | ||||||
Differentiated | 53 | 18 | 3 | 8 | 24 | 66.0 | ||
Undifferentiated | 60 | 33 | 10 | 3 | 14 | 45.0 |
- Citation: Zheng HC, Li YL, Sun JM, Yang XF, Li XH, Jiang WG, Zhang YC, Xin Y. Growth, invasion, metastasis, differentiation, angiogenesis and apoptosis of gastric cancer regulated by expression of PTEN encoding products. World J Gastroenterol 2003; 9(8): 1662-1666
- URL: https://www.wjgnet.com/1007-9327/full/v9/i8/1662.htm
- DOI: https://dx.doi.org/10.3748/wjg.v9.i8.1662