Density of Helicobacter pylori may affect the efficacy of eradication therapy and ulcer healing in patients with active duodenal ulcers

Table 3 Healing rates of duodenal ulcer and the density of H. pylori

	Healing rates	95%CI	P value
Intention-to-treat
H. pylori density
Mild	32/36 (88.9%)	73.0%-96.4%
Moderate	33/35 (94.3%)	79.5%-99.0%
Marked	21/33 (63.6%)	45.1%-79.0%
Total	86/104 (82.7%)	73.8%-89.2%	0.002a
Per Protocol
H. pylori density
Mild	32/32 (100.0%)	86.7%-100.0%
Moderate	33/33 (100.0%)	87.2%-100.0%
Marked	21/27 (77.8%)	57.3%-90.6%
Total	86/92 (93.5%)	85.8%-97.3%	< 0.001b

Notes:

^aBased on χ² test;

^bBased on Fisher's exact test.