Esophageal Cancer
Copyright ©The Author(s) 2003.
World J Gastroenterol. Jul 15, 2003; 9(7): 1394-1397
Published online Jul 15, 2003. doi: 10.3748/wjg.v9.i7.1394
Table 1 Distribution of CYP1A1 genetic polymorphism in controls and subjects with cancer and different severity of lesions n(%)
Control (n = 38)BCH (n = 30)DYS (n = 32)ESCC (n = 62)
CYP1A1 3'
Wild type12 (32)8 (27)9 (28)33 (53)
Heterozygous22 (58)16 (53)17 (53)25 (40)
Homozygous variant4 (10)3 (10)3 (9)4 (6)
Heterozygous+Homozygous26 (68)19 (63)20 (62)29 (47)a
CYP1A1 exon 7
Ile/Ile20 (53)14 (47)16 (50)30 (48)
Val/Ile16 (42)14 (47)15 (47)28 (45)
Val/Val2 (5)2 (7)1 (3)4 (6)
Val/Ile + Val/Val18 (47)16 (53)16 (50)32 (52)