Celecoxib inhibits proliferation and induces apoptosis via prostaglandin E2 pathway in human cholangiocarcinoma cell lines

doi:10.3748/wjg.v9.i6.1302

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Jun 15, 2003 (publication date) through Jul 20, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 15, 2003; 9(6): 1302-1306
Published online Jun 15, 2003. doi: 10.3748/wjg.v9.i6.1302

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Figure 4 Cell cycle analysis. Representative flow cytometry data from QBC939 cells after 48 h in the presence of various concentration of celecoxib: 0 μmol/L (A), 10 μmol/L (B), 20 μmol/L (C) and 40 μmol/L (D). The percentage of QBC939 cells in G₀-G₁ phase after treatment with 40 μmol/L (74.66 ± 6.21) and 20 μmol/L (68.63 ± 4.36) of celecoxib increased significantly compared with control cells (t test, P < 0.01).

Citation: Wu GS, Zou SQ, Liu ZR, Tang ZH, Wang JH. Celecoxib inhibits proliferation and induces apoptosis via prostaglandin E₂ pathway in human cholangiocarcinoma cell lines. World J Gastroenterol 2003; 9(6): 1302-1306
URL: https://www.wjgnet.com/1007-9327/full/v9/i6/1302.htm
DOI: https://dx.doi.org/10.3748/wjg.v9.i6.1302