Synergistic antitumor effect of TRAIL and doxorubicin on colon cancer cell line SW480

doi:10.3748/wjg.v9.i6.1241

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Jun 15, 2003 (publication date) through Nov 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Colorectal Cancer

World J Gastroenterol. Jun 15, 2003; 9(6): 1241-1245
Published online Jun 15, 2003. doi: 10.3748/wjg.v9.i6.1241

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Figure 1 Effect of TRAIL on SW480 cells. SW480 cells were treated with TRAIL at the concentrations of 0, 10, 100, 500 and 1000 μg•l^-1 for 24 h. Cell growth inhibition was assessed by MTT assay and confirmed by flow cytometry assay. Compared with TRAIL-sensitive leukaemic cell line Jurkat (IC₅₀ 0.42 μg•l^-1), SW480 cells (IC₅₀ > 1000 μg•l^-1) were not responsive to TRAIL at concentration more than 100 times those active on Jurkat.

Citation: Xu LH, Deng CS, Zhu YQ, Liu SQ, Liu DZ. Synergistic antitumor effect of TRAIL and doxorubicin on colon cancer cell line SW480. World J Gastroenterol 2003; 9(6): 1241-1245
URL: https://www.wjgnet.com/1007-9327/full/v9/i6/1241.htm
DOI: https://dx.doi.org/10.3748/wjg.v9.i6.1241