Detection of human papillomavirus in Chinese esophageal squamous cell carcinoma and its adjacent normal epithelium

doi:10.3748/wjg.v9.i6.1170

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Jun 15, 2003 (publication date) through Feb 8, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Esophageal Cancer

World J Gastroenterol. Jun 15, 2003; 9(6): 1170-1173
Published online Jun 15, 2003. doi: 10.3748/wjg.v9.i6.1170

Table 1 HPV-16 infection rate detected by PCR, ISH and IHC in normal and tumor esophageal epithelium from two high-incidence regions in China

Samples	Region	n	PCR	ISH	IHC
Normal	Shanxi	23	8 (34.7%)^a	6 (26.1%)	1 (4.3%)^a
Tumor	Shanxi	23	11 (47.8%)	6 (26.1%)	5 (21.7%)
	Anyang	25	20 (80.0%)	13 (52.0%)	8 (32.0%)
Total		48	31 (64.6%)	19 (39.6%)	13 (27.1%)

^aP < 0.05, from PCR and IHC data, HPV infection rate in normal esophageal epithelium was distinctly different from those in esophageal cancer samples.

Citation: Zhou XB, Guo M, Quan LP, Zhang W, Lu ZM, Wang QH, Ke Y, Xu NZ. Detection of human papillomavirus in Chinese esophageal squamous cell carcinoma and its adjacent normal epithelium. World J Gastroenterol 2003; 9(6): 1170-1173
URL: https://www.wjgnet.com/1007-9327/full/v9/i6/1170.htm
DOI: https://dx.doi.org/10.3748/wjg.v9.i6.1170