Imbalance between expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in invasiveness and metastasis of human gastric carcinoma

Table 3 Association between the expression of MMP-9 (matrix metalloproteinase-9) and TIMP-1 (tissue inhibitor of metalloproteinase-1) and the prognosis of patients with gastric carcinoma

	n	Survival (%)			P value
		1 yr	2 yr	5 yr
MMP-9 expression
-	50	80.42	70.33	60.92	> 0.05
+	117	68.09	55.77	44.15
TIMP-1 expression
-	121	67.48	56.62	41.23	> 0.05
+	46	82.93	68.81	68.81
Co-expression of
MMP-9 and TIMP-1
A	83	64.87	53.62	36.75	< 0.05
B	34	76.08	60.90	60.90
C	38	73.48	63.74	49.42
D	12	100.00	88.89	88.89a

Note: A: MMP-9(+)TIMP-1(-); B: MMP-9(+)TIMP-1(+); C: MMP-9(-)TIMP-1(-); D: MMP-9(-)TIMP-1(+),

^aP < 0.05 vs A.