Pleckstrin homology domain of G protein-coupled receptor kinase-2 binds to PKC and affects the activity of PKC kinase

doi:10.3748/wjg.v9.i4.800

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Apr 15, 2003 (publication date) through Feb 24, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 15, 2003; 9(4): 800-803
Published online Apr 15, 2003. doi: 10.3748/wjg.v9.i4.800

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Figure 3 After stimulation of epinephrine, Co-immunopre-cipitation was performed with anti-GRK₂ and anti-PKC in co-precipitation and detection of PKC and GRK₂. Lane 1 was PKC detected in precipitate of GRK antibody, lane 2 was GRK₂ de-tected in precipitate of PKC antibody. Lane 3 indicated the PKC did not bind to GRK₂ in the intact cells without stimulation of epinephrine , lane 4 was the lysate of Jurkat cell.

Citation: Yang XL, Zhang YL, Lai ZS, Xing FY, Liu YH. Pleckstrin homology domain of G protein-coupled receptor kinase-2 binds to PKC and affects the activity of PKC kinase. World J Gastroenterol 2003; 9(4): 800-803
URL: https://www.wjgnet.com/1007-9327/full/v9/i4/800.htm
DOI: https://dx.doi.org/10.3748/wjg.v9.i4.800