Effect of transforming growth factor beta and bone morphogenetic proteins on rat hepatic stellate cell proliferation and trans-differentiation

Figure 3 Regulating effect of BMP-2 and BMP-4 on hepatic stellate cell trans-differentiation. Hepatic stellate cells were in-cubated with different concentrations of BMP-2 or BMP-4 for three days. The media and BMPs were changed every other day. Western blot was performed as described in Materials and methods. The top panel represents typical Western blot of SMA. The lower panel represents histogram of densitometric data from four-separated Western blot (mean ± SE).