Copyright
©The Author(s) 2003.
World J Gastroenterol. Mar 15, 2003; 9(3): 578-583
Published online Mar 15, 2003. doi: 10.3748/wjg.v9.i3.578
Published online Mar 15, 2003. doi: 10.3748/wjg.v9.i3.578
Table 4 Schematic diagram of the distribution of deletion within nine exons of the human HPRT gene
Types of exons deletion | Mutation clones | |||||||||
1 | 2 | 3 | 4 | 5 | 6 | 7/8 | 9 | Number | Percent (%) | |
Spontaneous mutants | 12 | 92.3 | ||||||||
—a | 1 | 7.7 | ||||||||
ENU-induced mutants | 12 | 20.3 | ||||||||
— | 3 | 5.1 | ||||||||
— | 2 | 3.4 | ||||||||
— | — | 4 | 6.8 | |||||||
— | 2 | 3.4 | ||||||||
— | — | 1 | 1.7 | |||||||
— | — | — | 2 | 3.4 | ||||||
— | — | — | 2 | 3.4 | ||||||
— | — | — | — | 2 | 3.4 | |||||
— | — | — | 1 | 1.7 | ||||||
— | — | — | — | 1 | 1.7 | |||||
— | — | — | — | — | 3 | 5.1 | ||||
— | — | — | — | — | — | — | 1 | 1.7 | ||
— | — | — | — | — | — | — | — | 16 | 27.1 | |
— | — | — | — | — | 1 | 1.7 | ||||
— | — | — | — | 1 | 1.7 | |||||
— | — | 2 | 3.4 | |||||||
— | — | — | — | 2 | 3.4 | |||||
— | — | 1 | 1.7 | |||||||
r-rays-induced mutants | 18 | 38.3 | ||||||||
— | 1 | 2.1 | ||||||||
— | — | 1 | 2.1 | |||||||
— | — | 2 | 4.3 | |||||||
— | — | — | 2 | 4.3 | ||||||
— | — | — | 1 | 2.1 | ||||||
— | — | — | — | 1 | 2.1 | |||||
— | — | — | — | 3 | 6.4 | |||||
— | — | — | — | — | 1 | 2.1 | ||||
— | — | — | — | — | 1 | 2.1 | ||||
— | — | — | — | — | — | — | 2 | 4.3 | ||
— | — | — | — | — | — | — | — | 14 | 29.8 |
- Citation: Liu SX, Cao J, An H, Shun HM, Yang LJ, Liu Y. Analysis of spontaneous, gamma ray- and ethylnitrosourea-induced hprt mutants in HL-60 cells with multiplex PCR. World J Gastroenterol 2003; 9(3): 578-583
- URL: https://www.wjgnet.com/1007-9327/full/v9/i3/578.htm
- DOI: https://dx.doi.org/10.3748/wjg.v9.i3.578