Effect of cisapride on intestinal bacterial and endotoxin translocation in cirrhosis

Table 4 Effect of cisapride on BT, IBO, serum endotoxin level, intestinal transit and intestinal permeability of cirrhotic rats

	Placebo	Cisapride
Number of animal	20	20
Bacterial translocation (%)	11/20(55%)	2/20(10%)b
IBO(%)	16/20(80%)	3/20(15%)b
Total jejunal bacteria contents (CFU/mL)	1.60 ± 0.42	0.60 ± 0.58a
Endotoxin level(pg/mL)	0.721 ± 0.123	0.148 ± 0.079b
Intestinal transit (geometric center ratio)	0.33 ± 0.08	0.68 ± 0.16b
Intestinal permeability (%urinary excretion of 99mTc-DTPA)	17.2 ± 5.98	12.2 ± 5.28a

^bP < 0.01 vs placebo;

^aP < 0.05 vs placebo.