Expression and significance of PTEN, hypoxia-inducible factor-1 alpha in colorectal adenoma and adenocarcinoma

Table 1 Correlation between expressions of PENT, HIF-1α, VEGF and Dukes stages of colorectal adenocarcinoma

Dukes stage	n	PTEN( -x ± s)	HIF-1 ( -x ± s)	VEGF( -x ± s)
A	17	0.1782 ± 0.0271ab	0.1029 ± 0.0457ac	0.1207 ± 0.0436ac
B	18	0.1583 ± 0.0397b	0.1656 ± 0.0329c	0.1772 ± 0.0514c
C+D	27	0.1470 ± 0.0524	0.2335 ± 0.0748	0.2219 ± 0.0803

^aP<0.05, vs Dukes stage B;

^bP < 0.05, vs Dukes stage C + D;

^cP < 0.01, vs Dukes stage C+D.