Copyright
©The Author(s) 2003.
World J Gastroenterol. Feb 15, 2003; 9(2): 320-323
Published online Feb 15, 2003. doi: 10.3748/wjg.v9.i2.320
Published online Feb 15, 2003. doi: 10.3748/wjg.v9.i2.320
Groups | Dose (mg·kg-1) | PlasmaNO (μM) | Liver homogenates | |
MDA (nmol/g tissue) | GSHpx (μ/mg protein) | |||
Normal | 8.8 ± 1.0 | 133.2 ± 14.5 | 163.9 ± 15.9 | |
Model | 74.5 ± 10.1d | 395.9 ± 23.6d | 62.5 ± 8.8d | |
Leflunomide | 4 | 68.3 ± 8.5d | 385.7 ± 22.2d | 66.3 ± 9.1d |
12 | 60.7 ± 7.1bd | 363.9 ± 19.3bd | 87.1 ± 9.9bd | |
36 | 55.3 ± 6.2bd | 301.9 ± 17.1bd | 95.1 ± 10.7bd | |
Prednisone | 3 | 44.4 ± 5.3bd | 272.0 ± 15.7bd | 108.0 ± 12.0bd |
- Citation: Yao HW, Li J, Jin Y, Zhang YF, Li CY, Xu SY. Effect of leflunomide on immunological liver injury in mice. World J Gastroenterol 2003; 9(2): 320-323
- URL: https://www.wjgnet.com/1007-9327/full/v9/i2/320.htm
- DOI: https://dx.doi.org/10.3748/wjg.v9.i2.320