Expression of e-cadherin and β-catenin in human esophageal squamous cell carcinoma: relationships with prognosis

Table 3 Multivariate results in Cox proportional hazards analysis for patients with ESCC

Variables	Category (Value)	β	Wald	P Value	HR	95%CI
Overall survival (n = 106)
location (mid-thoracic)	No/Yes (0/l)	0.650	5.665	0.017	1.916	1.112-3.272
Lymph node metastasis	No/Yes (0/l)	0.599	5.893	0.015	1.821	1.1222-953
Venous invasion	No/Yes (0/l)	1.147	18.633	< 0.00l	3.148	1.870-5.229
Clinical staging	I/II/III/IV (0/1/2/3)	0.420	8.475	0.004	1.521	1.147-2.018
E-cadherin	-/ ± /+ (0/1/2)	-0.431	5.687	0.017	0.650	0.456-0.926
Disease-free survival (n = 96)
Gender	M/F (0/1)	0.675	4.786	0.029	1.965	1.073-3.598
Tumor size	Continue	0.179	4.302	0.038	1.196	1.010-1.417
Clinical staging	I/II/III/IV (0/1/2/3)	0.272	3.233	0.042	1.313	0.976-1.767
Location (mid-thoracic)	No/Yes (0/l)	0.615	4.111	0.043	1.849	1.021-3.349
Venous invasion	No/Yes (0/l)	0.982	9.797	0.002	2.671	1.444--4.942
E-cadherin	-/ ± /+ (0/1/2)	-0.397	4.479	0.034	0.672	0.465-0.971