Spider angiomas in patients with liver cirrhosis: Role of vascular endothelial growth factor and basic fibroblast growth factor

Table 4 Univariate analysis of predictive factors for spider angiomas

Parameters	Odds ratio	95% Confidence interval	P Value
Age ( ≤ 60 years)	5.12	1.97-13.28	0.001
Albumin ( ≥ 3.7 g/dL)	0.66	0.27-1.64	0.369
Creatinine ( > 1.5 mg/dL)	0.58	0.06-5.81	0.642
AST ( > 45 U/L)	5.76	1.56-21.3	0.009
ALT ( > 40 U/L)	1.24	0.51-3.02	0.634
Bilirubin ( > 1.6 mg/dL)	2.71	1.09-6.74	0.031
Platelet count ( > 150000/uL)	1.41	0.44-4.52	0.563
Prothrombin time	2.96	1.15-7.58	0.024
prolongation ( > 4 s)
Child-Pugh score C	1.64	0.59-4.53	0.344
VEGF ( ≥ 134 pg/mL)	5.33	1.93-14.74	0.001
bFGF ( ≥ 4.8 pg/mL)	4.38	1.67-11.5	0.003
Alcoholism	3.29	1.25-8.67	0.016

AST = aspartate transaminase, ALT = alanine transaminase, VEGF = vascular endothelial growth factor, bFGF = basic fibro-blast growth factor.