Spider angiomas in patients with liver cirrhosis: Role of vascular endothelial growth factor and basic fibroblast growth factor

Table 2 Characteristics of patients’

	No. of patients	VEGF (pg/ml)	bFGF (pg/ml)
Sex
Male	67	121 ± 14	4.8 ± 0.5
Female	19	123 ± 27	6.1 ± 1.5
Age
≤ 60 years	36	149 ± 24	5.2 ± 0.8
> 60 years	50	103 ± 13	5.1 ± 0.6
Etiology
Alcohol-related	26	167 ± 29*	4.6 ± 0.7
Non-alcoholic	60	103 ± 13	5.4 ± 0.6
Albumin (g/dL)
≤ 3.6	48	132 ± 15	5.1 ± 0.7
> 3.6	38	109 ± 21	5.2 ± 0.7
Creatinine (mg/dL)
≤ 1.5	83	122 ± 13	5.2 ± 0.5
> 1.5	3	125 ± 73	4.5 ± 2.6
ALT (U/L)
≤ 40	37	136 ± 22	4.1 ± 0.6
> 40	49	111 ± 15	5.9 ± 0.7
Total bilirubin (mg/dL)
≤ 1.6	54	115 ± 16	5.2 ± 0.6
> 1.6	32	133 ± 20	5.0 ± 0.9
Child-Pugh score
A	47	98 ± 19	5.5 ± 0.7
B, C	39	141 ± 16	4.8 ± 0.7
Prothrombin time prolongation > 4 s
Yes	27	145 ± 23	5.0 ± 1.0
No	59	112 ± 15	5.3 ± 0.6
Platelet count (/μL)
≤ 150000	71	109 ± 12†	6.8 ± 1.5
> 150000	15	204 ± 41	4.7 ± 0.5
Esophageal varices
Yes	59	122 ± 14	5.0 ± 0.6
No	27	119 ± 28	5.8 ± 1.0
Spider angioma
Yes	31	185 ± 28b	6.8 ± 1.0a
No	55	90 ± 10	4.1 ± 0.5

Data were presented as mean ± SD.

^aP < 0.05,

^bP < 0.005. VEGF = vascular endothelial growth factor, bFGF = basic fibro-blast growth factor.