Identification of alkA gene related to virulence of Shigella flexneri 2a by mutational analysis

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Dec 15, 2003 (publication date) through Nov 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 15, 2003; 9(12): 2720-2725
Published online Dec 15, 2003. doi: 10.3748/wjg.v9.i12.2720

Table 2 BLAST analysis of S. flexneri 2a alkA gene

Bacteria	Gene product	Gene function	Identities (%)
Escherichia coli K12	3-methyl-adenine DNA glycosylase II	DNA - replication, repair, restriction/modification	97%
Escherichia coli O157:H7	3-methyl-adenine DNA glycosylase II	Macromolecule synthesis, modification: DNA - replication, repair, restriction/modification	97%
Salmonella typhimurium	3-methyl-adenine DNA glycosylase II	Unknown	74%
Ralstonia solanacearum	putative transcription regulator protein	Miscellaneous; not classified regulator	38%
Pseudomonas aeruginosa	DNA-3-methyladenine glycosidase II	Unknown	37%
Xanthomonas axonopodis	DNA methylation and regulatory protein	Unknown	35%
Mycobacterium bovis	Methylated-DNA—protein-cysteine methyltransferase	Adaptative response	34%
Mycobacterium tuberculosis	alkA protein	Unknown	34%
Vibrio cholerae	ada regulatory protein	Unknown	32%
Bacillus anthracis	DNA-3-methyladenine glycosidase	Unknown	32%
Archaeoglobus fulgidus	3-methyladenine DNA glycosylase	DNA repair at suboptimal and maybe even mesophilic temperatures	30%

Citation: Shi ZX, Wang HL, Hu K, Feng EL, Yao X, Su GF, Huang PT, Huang LY. Identification of alkA gene related to virulence of Shigella flexneri 2a by mutational analysis. World J Gastroenterol 2003; 9(12): 2720-2725
URL: https://www.wjgnet.com/1007-9327/full/v9/i12/2720.htm
DOI: https://dx.doi.org/10.3748/wjg.v9.i12.2720