Lack of inhibitory effects of Lactic acid bacteria on 1,2-dimethylhydrazine-induced colon tumors in rats

doi:10.3748/wjg.v9.i11.2469

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Nov 15, 2003 (publication date) through Nov 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Colorectal Cancer

World J Gastroenterol. Nov 15, 2003; 9(11): 2469-2473
Published online Nov 15, 2003. doi: 10.3748/wjg.v9.i11.2469

Table 2 Colon tumor incidence, classification, multiplicity, tumor volume and stage in rats treated with DMH followed or not by lactic acid bacteria (22wk)^a

Treatment	Incidencen (%)	Total no.tumors	Adenoma No (%)	*Carcinoma in situ* No (%)**	Carcinoma No (%)	Multiplicity^b No.	Tumor volumemm³	Duke’s stagec
Treatment	Incidencen (%)	Total no.tumors	Adenoma No (%)	*Carcinoma in situ* No (%)**	Carcinoma No (%)	Multiplicity^b No.	Tumor volumemm³	A	B	C
DMH + lactic acid	9 (90)	28	12 (43)	8 (28.5)	8 (28.5)	3.11 ± 2.00	1.64 ± 1.92	0	2	1
DMH	10 (100)	40	27 (67.5)	3 (7.5)	10 (25)	4.00 ± 2.96	4.31 ± 4.56	0	0	3

a: Values are means ± SD. b: No. of tumors/tumor-bearing rat. c: No. of rats with carcinoma were allocated to one of three tumor stages.

Citation: Li W, Li CB. Lack of inhibitory effects of Lactic acid bacteria on 1,2-dimethylhydrazine-induced colon tumors in rats. World J Gastroenterol 2003; 9(11): 2469-2473
URL: https://www.wjgnet.com/1007-9327/full/v9/i11/2469.htm
DOI: https://dx.doi.org/10.3748/wjg.v9.i11.2469