Pan-enteric dysmotility, impaired quality of life and alexithymia in a large group of patients meeting ROME II criteria for irritable bowel syndrome

Figure 3 Time-course of visual analogue scale (VAS) for appetite, satiety, nausea, abdominal fullness and epigastric pain (or discomfort) in healthy subjects. On the X-axis time “0” is before ingestion of test meal. Asterisks indicate significant differences (0.0001 < P < 0.001) of IBS patients vs healthy subjects at baseline. Significant differences for nausea, fullness and epi-gastric pain/discomfort of IBS patients vs healthy subjects (area under curve).