Effect of oral epidermal growth factor on mucosal healing in rats with duodenal ulcer

Table 4 Duodenal mucosal EGF content in sham operation and duodenal ulcer rats with or without oral EGF¹

Group	Sham operation		Duodenal ulcer
	-EGF	+EGF	-EGF	+EGF
	Duodenal mucosal EGF (ng/g mucosa)
Day 5	35.7 ± 12.9ab	76.0 ± 13.7c	28.3 ± 9.2a	68.3 ± 10.9bc
Day 15	84.8 ± 22.8a†	47.5 ± 19.3ab	12.9 ± 3.9b*	28.3 ± 10.5b†

¹Data are mean ± SE (n = 6). Values in a row not sharing a su-perscript letter were significantly different (P < 0.05) by Fisher’s least significant difference test. ^*The content of EGF in duode-nal mucosa was significantly different (P < 0.05) from that in the control group (61.1 ± 5.4 ng/g mucosa, n = 6) on day 0 by Dunnett’s test. ^†P < 0.05 compared with day 5 within the same group by Fisher’s least significant difference test.