Effect of oral epidermal growth factor on mucosal healing in rats with duodenal ulcer

Table 3 Duodenal mucosal DNA, RNA, and protein contents in sham operation and duodenal ulcer rats with or without oral EGF¹

Group	Sham operation		Duodenal ulcer
	-EGF	+EGF	-EGF	+EGF
	Duodenal mucosal DNA (mg/g mucosa)
Day 5	1.06 ± 0.20a	1.51 ± 0.57a	1.31 ± 0.45a	0.70 ± 0.25a
Day 15	2.96 ± 1.27a*†	1.77 ± 0.64a	1.45 ± 0.52a	6.44 ± 0.54b*†
	Duodenal mucosal RNA (mg/g mucosa)
Day 5	4.89 ± 0.42a	7.10 ± 0.20b	4.71 ± 0.35a*	3.32 ± 0.82a*
Day 15	5.24 ± 1.60a	6.00 ± 0.30a	5.38 ± 0.44a	4.79 ± 0.91a
	Duodenal mucosal protein (mg/g mucosa)
Day 5	49.8 ± 2.9a*	20.5 ± 5.4b	22.7 ± 2.8b	25.5 ± 3.3b
Day 15	25.2 ± 2.8a†	19.3 ± 2.7a	24.3 ± 1.6a	26.2 ± 1.3a

¹Data are mean ± SE (n = 6). Values in a row not sharing a su-perscript letter were significantly different (P < 0.05) by Fisher’s least significant difference test. ^*The contents of DNA, RNA, and protein in duodenal mucosa were significantly different (P < 0.05) from those in the control group (0.86 ± 0.06 mg/g, 6.57 ± 0.40 mg/g, 25.1 ± 1.4 mg/g mucosa, n = 6) on day 0 by Dunnett’s test. ^†P < 0.05 compared with day 5 within the same group by Fisher’s least significant difference test.