Association between HLA class II gene and susceptibility or resistance to chronic hepatitis B

Table 3 Allele frequency of HLA-DQB1 in patients with chronic and acute hepatitis B and normal heathy individuals

HLA-DQB1 allele	Normal control (n = 106)		Chronic hepatitis B (n = 52)		Acute hepatitis B (n = 30)
	PN	AF	PN	AF	PN	AF
0201	23	10.85	10	9.62	6	10.00
0301*	40	18.87	37	35.58	16	26.67
0302	14	6.61	6	5.77	3	5.00
0303	35	16.51	15	14.42	10	16.67
0401	11	5.19	5	4.81	3	5.00
0402	2	0.94	1	0.96	1	1.67
0501	9	4.25	3	2.88	2	3.33
0502	20	9.43	7	6.73	3	5.00
0503	6	2.83	2	1.92	1	1.67
0601	20	9.43	7	6.73	7	11.67
0602	12	5.66	4	3.85	3	5.00
0603	5	2.36	2	1.92	1	1.67
0604	7	3.30	2	1.92	2	3.33
Blank	8	3.77	3	2.89	2	3.33

PN: Positive number, AF: Allele frequency. χ² = 15.5938, Pc = 0.0075, RR = 4.07.