Gene expression profiles at different stages of human esophageal squamous cell carcinoma

Table 1 Ratio of expression level for a set of genes with the largest loading scores in the first two principal components

Component 1			Component 2
Gene	Ratio ELCA/LaCa	Ratio BCH/N	Gene	Ratio BCH/N	Ratio DYS/CAIN
GAF	131	16	PCTK1	122	8
CAPR	582	25	DAXX	5	95
CASP8	743	37	P70	7	62
MMP16	143	17	CCNH	174	87
DCC Precursor	316	12	CD153 antigen	70	31
Tenascin-R	742	21	TLAA	9	39
ZAP70	157	83	XPG	90	26
IL-13	110	22	Apoptosis Inhibitor Survivin	3	107
TRAIL receptor	66	82	Bcl-1 oncogene	122	19
	LaCa/ELCA	N/BCH		N/BCH	CAIN/DYS
BMP5	284	170	MERLIN	3	411
MIF	79	72	LERK-8	31	334
N-myc	14	110	DSG2; HDGC	355	395
RPSA	19	68	MMP11	2	271
RBL2	33	18	CDK2	13	51
RAD52	27	9	CLK1	60	798
RBQ1	15	55	MDMX	3	225

N: Normal; BCH: Basel cell hyperplasia; DYS: Dysplasia; CAIN: Carcinoma in situ; ELCA: Early cancer; LaCa: Late cancer.