Liver Cancer
Copyright ©The Author(s) 2003.
World J Gastroenterol. Jan 15, 2003; 9(1): 89-93
Published online Jan 15, 2003. doi: 10.3748/wjg.v9.i1.89
Table 2 The alterations of LPTS-S and LPTS-L in tumor cell lines
Cell lineCell typeMutationExonCodonPredicted effect
CCLP1CholangiocarcinomaC161TExon 2gct→gttAla→Val
HepG2HCCA701A, G(LPTS-S)Exon 7Outside ORF/
A778A, G(LPTS-L)aca→gcaThr→Ala
HepT1HCCC183TExon 2gcc→gctAla
MEKHCCA701A, G(LPTS-S)Exon 7Outside ORF/
A778A, G(LPTS-L)aca→gcaThr→Ala
SNU182HCCA701A, G(LPTS-S)Exon 7Outside ORF/
A778A, G(LPTS-L)aca→gcaThr→Ala
Li7AHCCA803T (LPTS-S)Exon 7Outside ORF/
A880T (LPTS-L)agc→tgcSer→Cys
Li21HCCC183TExon 2gcc→gctAla
A803T (LPTS-S)Exon 7Outside ORF/
A880T (LPTS-L)agc→tgcSer→Cys
MZCHA1HCCA803T (LPTS-S)Exon 7Outside ORF/
A880T (LPTS-L)agc→tgcSer→Cys
PCI-SG231HCCG111CExon 1Before ATG/
A803T (LPTS-S)Exon 7Outside ORF/
A880T (LPTS-L)agc→tgcSer→Cys
PLCPRF5HCCA497GExon5tat→tgtTyr→Cys
IGR-OV1Ovarian tumorA701A, G (LPTS-S)Exon 7Outside ORF/
A778A, G (LPTS-L)aca→gcaThr→Ala
SW579Head and neck tumorC183C, TExon 2gcc→gctAla